Key Insights

Highlights

Success Rate

43% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 85/100

Termination Rate

19.0%

4 terminated out of 21 trials

Success Rate

42.9%

-43.6% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 3 completed with results

Key Signals

43% success

Data Visualizations

Phase Distribution

19Total
Early P 1 (1)
P 1 (13)
P 2 (5)

Trial Status

Recruiting5
Active Not Recruiting5
Terminated4
Unknown3
Completed3
Not Yet Recruiting1

Trial Success Rate

42.9%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT06552559Phase 1Recruiting

Selinexor With ICE Chemotherapy in Secondary Central Nervous System Involving B-cell Non-Hodgkin Lymphoma

NCT03853616Phase 1Active Not Recruiting

MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM)

NCT07319676Phase 1RecruitingPrimary

Antigen Targeted T Cell Therapy for Relapsed/Refractory B Cell Lymphomas

NCT04531046Phase 2Active Not RecruitingPrimary

Axi-Cel as a 2nd Line Therapy in Patients With Relapsed/Refractory Aggressive B Lymphoma Ineligible to Autologous Stem Cell Transplantation

NCT07321301Phase 2RecruitingPrimary

Polymer-lipid Particle-delivered CAR1920 mRNA CAR-T Therapy for Relapsed/Refractory B-cell Lymphoma/Leukemia

NCT05705570Phase 1Recruiting

Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies

NCT06912529Phase 2TerminatedPrimary

Axicabtagene Ciloleucel CAR T-cells in Patients With Relapsed or Refractory Primary Mediastinal B-cell Lymphoma

NCT06220097Phase 2Active Not Recruiting

Mitoxantrone Hydrochloride Liposome Injection-containing Bridging Regimen and CD19-targeting CAR-T Therapies

NCT05318963Phase 1Terminated

Targeting CD19/CD20/CD22 Triple-targeted Cell in Patients With Relapsed/Refractory B-cell Lymphoma

NCT03664635Phase 1Completed

MB-CART20.1 Lymphoma

NCT05645744Terminated

Long-term Follow-up Study in Patients Previously Treated With a Mustang Bio CAR-T Cell Investigational Product.

NCT05360238Phase 1Terminated

Study to Assess Safety, Tolerability and Efficacy of MB-106 in Patients With Relapsed or Refractory B-Cell NHL or CLL

NCT06445803Phase 1Recruiting

CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL

NCT04304040Phase 1Active Not Recruiting

A Study of MIL62 Combined With Orelabrutinib for the Treatment of R/R CD20+B Cell Lymphoma

NCT05909098Phase 1Not Yet Recruiting

Safety and Efficacy of Autologous NK Cell Adjuvant Therapy for Relapsed/Refractory Non-Hodgkin's B-cell Lymphoma

NCT05130489Completed

CAR T Cell Therapy Related Cardiovascular Outcomes

NCT04214886Phase 1Active Not Recruiting

CD19 Chimeric Antigen Receptor (CAR) T Cells for Adults With Recurrent or Refractory B Cell Malignancies

NCT04747093Phase 1Unknown

Induced-T Cell Like NK Cells for B Cell Malignancies

NCT04303247Early Phase 1UnknownPrimary

CD19 and CD22 Dual-targeted CAR-T Cells for Relapsed or Refractory B-NHL

NCT01535989Phase 1CompletedPrimary

Study of Inotuzumab Ozogamicin + Temsirolimus in Patients With Relapsed or Refractory CD22+ B-cell NHLymphoma

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