Key Insights

Highlights

Success Rate

77% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

10.7%

3 terminated out of 28 trials

Success Rate

76.9%

-9.6% vs benchmark

Late-Stage Pipeline

14%

4 trials in Phase 3/4

Results Transparency

40%

4 of 10 completed with results

Key Signals

4 with results77% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (7)
Early P 1 (1)
P 1 (2)
P 2 (5)
P 3 (3)
P 4 (1)

Trial Status

Completed10
Unknown10
Terminated3
Active Not Recruiting2
Not Yet Recruiting2
Withdrawn1

Trial Success Rate

76.9%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (28)

Showing 20 of 20 trials
NCT06664853Phase 3TerminatedPrimary

Open-Label Extension of EryDex Study IEDAT-04-2022

NCT06193200Phase 3CompletedPrimary

Evaluate the Neurological Effects of EryDex on Subjects With A-T

NCT05692596Active Not Recruiting

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

NCT03759678Phase 2TerminatedPrimary

N-Acetyl-L-Leucine for Ataxia-Telangiectasia (A-T)

NCT07215416Phase 1Not Yet RecruitingPrimary

Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T)

NCT03563053Phase 3TerminatedPrimary

Extension Treatment Using EryDex System in Patients With AT Who Participated in the ATTeST-IEDAT-02-2015 Study

NCT06324877Not ApplicableNot Yet RecruitingPrimary

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside

NCT05252819CompletedPrimary

Whole Body MRI for Cancer Surveillance in A-T

NCT05692622Not ApplicableUnknown

Home-based Complex Intervention for Children With Ataxia Telangiectasia

NCT04513002Phase 2CompletedPrimary

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With a Novel Form of Anaplerosis

NCT05531890Phase 1UnknownPrimary

Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects

NCT04870866Phase 2Active Not RecruitingPrimary

NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia

NCT03962114Phase 2CompletedPrimary

Effects of Vitamin B3 in Patients With Ataxia Telangiectasia

NCT05471310CompletedPrimary

Videoocular Assessment of Eye Movement Activity in an Ataxia Telangiectasia

NCT04991701UnknownPrimary

A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia

NCT04037189UnknownPrimary

Treatment of Leukemia and Lymphoma in Children With Ataxia Telangiectasia

NCT02285348Not ApplicableCompletedPrimary

Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-T

NCT04887311Phase 2Unknown

MBM-01 (Tempol) for the Treatment of Ataxia Telangiectasia

NCT04605523UnknownPrimary

Neurofilament Light- Chain in Ataxia Telangiectasia

NCT02309632Not ApplicableWithdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

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