Key Insights

Highlights

Success Rate

82% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.3%

2 terminated out of 24 trials

Success Rate

81.8%

-4.7% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

33%

3 of 9 completed with results

Key Signals

3 with results82% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (4)
P 1 (11)
P 2 (4)
P 3 (1)

Trial Status

Completed9
Recruiting7
Withdrawn4
Terminated2
Not Yet Recruiting1
Active Not Recruiting1

Trial Success Rate

81.8%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT05789394Phase 1Recruiting

Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy

NCT07459101Not ApplicableRecruiting

UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-4

NCT05303519Phase 3Recruiting

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

NCT02709226Phase 1CompletedPrimary

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

NCT06614855Phase 1Active Not Recruiting

A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma

NCT05229198CompletedPrimary

ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas

NCT05375318CompletedPrimary

BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels

NCT02766699Phase 1Completed

A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent GBM

NCT06161974Phase 2Recruiting

Study of Olutasidenib and Temozolomide in HGG

NCT02465268Phase 2Completed

Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme

NCT06157541Phase 1Recruiting

T Cells and Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma

NCT06118723Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

NCT03861299Not ApplicableRecruiting

The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.

NCT02432417Phase 2Withdrawn

The Addition of Chloroquine to Chemoradiation for Glioblastoma,

NCT06017063Not ApplicableNot Yet Recruiting

Coaching for Coping in Glioblastoma Patients and Caregivers and Its Association With Compliance to TTFields

NCT04757662Phase 1Completed

Tadalafil to Overcome Immunosuppression During Chemoradiotherapy for IDH-wildtype Grade III-IV Astrocytoma

NCT02366728Phase 2Completed

DC Migration Study for Newly-Diagnosed GBM

NCT03956706Not ApplicableWithdrawn

Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas

NCT05218408Phase 1WithdrawnPrimary

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type

NCT03072134Phase 1Completed

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

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