Key Insights

Highlights

Success Rate

89% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

5.2%

3 terminated out of 58 trials

Success Rate

89.3%

+2.8% vs benchmark

Late-Stage Pipeline

22%

13 trials in Phase 3/4

Results Transparency

36%

9 of 25 completed with results

Key Signals

9 with results89% success

Data Visualizations

Phase Distribution

50Total
Not Applicable (25)
Early P 1 (1)
P 1 (5)
P 2 (6)
P 3 (6)
P 4 (7)

Trial Status

Completed25
Recruiting14
Unknown8
Not Yet Recruiting5
Terminated3
Active Not Recruiting1

Trial Success Rate

89.3%

Benchmark: 86.5%

Based on 25 completed trials

Clinical Trials (58)

Showing 20 of 20 trials
NCT07404410Not ApplicableRecruitingPrimary

Robotic Technologies for APATHy in Dementia: a Randomised Controlled Trial (RAPHAel)

NCT03190681Early Phase 1Completed

Motivation and Methylphenidate

NCT07146503Recruiting

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

NCT04573712Not ApplicableCompletedPrimary

The Effects of Apathy on Different Forms of Fatigue

NCT05505019Not ApplicableRecruiting

Targeting Apathy With Music in Parkinson's Disease

NCT07468305Not ApplicableNot Yet RecruitingPrimary

SENS'REM - SENSoriality and Multi-Sensory Emotional Reminiscences: a Pilot Study

NCT07461220Phase 1Recruiting

Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy

NCT07237009Recruiting

Effects of Personalized Digital Reminiscence Therapy on Patients With Neurocognitive Disorders

NCT06699628Phase 1Completed

Phase I Trial Evaluating the Pharmacokinetics of Single Ascending Oral Doses of IRL757 in Healthy Elderly Volunteers

NCT05182151TerminatedPrimary

Effect of Istradefylline Treatment on Behavioral Measures of Apathy in Parkinson's Disease.

NCT06642454Not ApplicableEnrolling By Invitation

A Randomized Double-Blind Active-Controlled Crossover Trial of Respiratory-Gated Versus Non-Gated Transcutaneous Auricular Vagus Nerve Stimulation for the Treatment of Motor and Non-Motor Symptoms in Parkinson's Disease

NCT06919094Not ApplicableRecruitingPrimary

A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults

NCT07279740Phase 2Recruiting

Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia

NCT05649176Not ApplicableCompleted

Lifestyle Intervention for Improving Insulin Resistance and Concern for Health

NCT05232877Not ApplicableActive Not RecruitingPrimary

Effects of t-DCS and Cognitive Training on Apathy in Elderly With Minor Neurocognitive Impairment

NCT03590327Not ApplicableCompletedPrimary

Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment

NCT07118956Not ApplicableRecruiting

Respiratory-gated Transcutaneous Auricular Vagus Nerve Stimulation for Improving Apathy in Parkinson's Disease

NCT02496312Not ApplicableCompletedPrimary

Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated.

NCT07113067Phase 1RecruitingPrimary

Accelerated rTMS vs. Sham for Stroke Apathy

NCT05877885Not ApplicableRecruiting

Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics

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