Key Insights

Highlights

Success Rate

85% trial completion

Published Results

16 trials with published results (9%)

Research Maturity

70 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.0%

12 terminated out of 171 trials

Success Rate

85.4%

-1.1% vs benchmark

Late-Stage Pipeline

7%

12 trials in Phase 3/4

Results Transparency

23%

16 of 70 completed with results

Key Signals

16 with results85% success12 terminated

Data Visualizations

Phase Distribution

84Total
Not Applicable (68)
P 2 (4)
P 3 (4)
P 4 (8)

Trial Status

Completed70
Unknown30
Recruiting26
Active Not Recruiting18
Terminated12
Not Yet Recruiting10

Trial Success Rate

85.4%

Benchmark: 86.5%

Based on 70 completed trials

Clinical Trials (171)

Showing 20 of 20 trials
NCT06510855Not ApplicableActive Not Recruiting

DurAVR™ THV EU-EFS

NCT06286358RecruitingPrimary

Aortopathy Relationship To Imagery and Kinocardiography Features (ARTIK)

NCT06506903Not ApplicableActive Not RecruitingPrimary

Avalus Ultra Post-Approval Study (PAS)

NCT06352671RecruitingPrimary

Prospective Long-Term Outcomes of a Standardized Ross Procedure

NCT07520591Not Yet RecruitingPrimary

Valvosoft Outcomes Registry for Real-World Evidence

NCT03924661Active Not RecruitingPrimary

SJM Masters HP 15mm Rotatable Mechanical Heart Valve as Aortic Valve Replacement Therapy

NCT04754217RecruitingPrimary

Valved Graft PMCF Study

NCT04864145Not ApplicableRecruitingPrimary

Transcatheter Self-expandable Valve Implantation for the Treatment of Severe Native Aortic Regurgitation

NCT07120048RecruitingPrimary

Real World Data Collection on the INSPIRIS RESILIA Aortic Valve

NCT06594705Not ApplicableRecruiting

The JenaValve ALIGN-AR LVAD Registry

NCT02153307Not ApplicableRecruitingPrimary

Ambulatory Electrocardiographic Monitoring for the Detection of High-Degree Atrio-Ventricular Block in Patients With New-onset PeRsistent LEft Bundle Branch Block After Transcatheter Aortic Valve Implantation. The "MARE" Study

NCT07366671Recruiting

SAvvywire for Pacing and Procedural Hemodynamics In Transcatheter Aortic Valve Replacement Evaluation

NCT04909424CompletedPrimary

Prevalence of Cutaneous Enterococci at Femoral Insertion Site in Transcatheter Aortic Valve Implantation (TAVI)

NCT06106451Not ApplicableCompletedPrimary

Optimization Post-TAVR to IMprove Activity Levels (OPTIMAL Study)

NCT03440697Active Not Recruiting

Pathogenetic Basis of Aortopathy and Aortic Valve Disease

NCT07276711Not ApplicableNot Yet Recruiting

CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material

NCT01194362CompletedPrimary

A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease

NCT03453567Active Not RecruitingPrimary

Evaluation of Effectiveness and Safety of Aortic Valve Replacement in Routine Clinical Practice

NCT05758909Active Not RecruitingPrimary

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation

NCT07267117Recruiting

Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease

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Research Network

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