Aortic Stenosis, Calcific
6
1
1
1
Key Insights
Highlights
Success Rate
100% trial completion (above average)
Treatment Research
6 treatments under study, led by Eplerenone
Research Leaders
14 sponsors active, led by Edwards Lifesciences
Related Conditions
Often studied with 4 related conditions
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 15/100
0.0%
0 terminated out of 6 trials
100.0%
+13.4% vs benchmark
17%
1 trials in Phase 3/4
100%
1 of 1 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 1 completed trials
Clinical Trials (6)
PCSK9 Inhibitors in the Treatment of Calcific Aortic Stenosis
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Prognostic Value of Myocardial Fibrosis in Severe Aortic Valve Stenosis
Accuracy of Using 2D Transesophageal Echocardiography Compared to Balloon Sizing in Determining Valve Size During Transcatheter Aortic Valve Implantation
Pressure Assessment to Improve Outcomes After TAVR: a Registry
Feasibility of Continuous Noninvasive Finger Arterial Blood Pressure Measurement for Detection and Staging of Aortic Stenosis
Research Network
Common Treatments
- Eplerenone1
- Cardiac Magnetic Resonance Imaging1
- Sapien 3 Sapien 3 Ultra Sapien 3 Ultra Resilia1
- Nexfin Measuremtents1
- Treatment With Pcsk9 Inhibitors1
Active Sponsors
- Edwards Lifesciences2
- Beijing Jishuitan Hospital1
- Malcom Randall VA Medical Center1
- North Florida Foundation for Research and Education1
- Peking University First Hospital1
Top Investigators
Leiden University Medical Center, Leiden, The Netherlands
Cedars-Sinai Medical Center, Los Angeles, CA, USA
Beijing Anzhen Hospital
Beijing Anzhen Hospital
University of Florida
Related Conditions
- Hypertension1
- Quality Of Life1
- Aortic Valve Stenosis1
- Heart Failure With Preserved Ejection Fraction1