Key Insights

Highlights

Success Rate

81% trial completion

Published Results

35 trials with published results (34%)

Research Maturity

62 completed trials (60% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.4%

15 terminated out of 104 trials

Success Rate

80.5%

-6.0% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

56%

35 of 62 completed with results

Key Signals

35 with results81% success15 terminated

Data Visualizations

Phase Distribution

100Total
Not Applicable (11)
Early P 1 (3)
P 1 (52)
P 2 (33)
P 3 (1)

Trial Status

Completed62
Terminated15
Unknown13
Suspended4
Recruiting4
Withdrawn3

Trial Success Rate

80.5%

Benchmark: 86.6%

Based on 62 completed trials

Clinical Trials (104)

Showing 20 of 20 trials
NCT04803201Phase 2SuspendedPrimary

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

NCT05377827Phase 1Suspended

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

NCT07388563Phase 1Suspended

Azacitidine and Abatacept in Relapsed or Refractory T-Cell Lymphoma

NCT07055477Phase 1Recruiting

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

NCT01787409Not ApplicableActive Not Recruiting

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

NCT02232516Phase 2Completed

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

NCT05978141Recruiting

A Registry for People With T-cell Lymphoma

NCT06561048Phase 3Recruiting

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

NCT06692452Phase 2Withdrawn

Tazemetostat Plus CHOP in 1L T-cell Lymphoma

NCT03590574Phase 1Terminated

Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma

NCT01199562Active Not Recruiting

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

NCT02588651Phase 2Completed

A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL)

NCT03113500Phase 2Active Not Recruiting

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma

NCT04234048Phase 1Recruiting

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

NCT05290155Phase 1Completed

Anti-CD7 CAR-T Cell Therapy for Relapse and Refractory CD7 Positive T Cell Malignancies

NCT03493451Phase 2Completed

Study of BGB-A317 in Participants With Relapsed or Refractory Mature T- and NK-cell Neoplasms

NCT02168140Phase 1Completed

CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

NCT06224842Phase 1UnknownPrimary

Clinical Study of Mitoxantrone Liposome and Azacitidine in the Treatment of R/R AITL

NCT01769222Phase 1Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

NCT04828174Phase 1Suspended

Anti-TRBC1 CAR-T Cell Therapy in Patients With TRBC1 Positive T Cell Malignancies

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