Key Insights

Highlights

Success Rate

80% trial completion

Published Results

35 trials with published results (34%)

Research Maturity

61 completed trials (59% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.4%

15 terminated out of 104 trials

Success Rate

80.3%

-6.2% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

57%

35 of 61 completed with results

Key Signals

35 with results80% success15 terminated

Data Visualizations

Phase Distribution

100Total
Not Applicable (11)
Early P 1 (3)
P 1 (52)
P 2 (33)
P 3 (1)

Trial Status

Completed61
Terminated15
Unknown13
Recruiting5
Active Not Recruiting5
Withdrawn3

Trial Success Rate

80.3%

Benchmark: 86.5%

Based on 61 completed trials

Clinical Trials (104)

Showing 20 of 20 trials
NCT04803201Phase 2SuspendedPrimary

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

NCT05377827Phase 1Active Not Recruiting

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

NCT06561048Phase 3Recruiting

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

NCT06692452Phase 2Withdrawn

Tazemetostat Plus CHOP in 1L T-cell Lymphoma

NCT07388563Phase 1Recruiting

Azacitidine and Abatacept in Relapsed or Refractory T-Cell Lymphoma

NCT03590574Phase 1Terminated

Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma

NCT07055477Phase 1Recruiting

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

NCT01199562Active Not Recruiting

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

NCT01787409Not ApplicableActive Not Recruiting

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

NCT02588651Phase 2Completed

A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL)

NCT03113500Phase 2Active Not Recruiting

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma

NCT04234048Phase 1Recruiting

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

NCT05290155Phase 1Completed

Anti-CD7 CAR-T Cell Therapy for Relapse and Refractory CD7 Positive T Cell Malignancies

NCT05978141Recruiting

A Registry for People With T-cell Lymphoma

NCT03493451Phase 2Completed

Study of BGB-A317 in Participants With Relapsed or Refractory Mature T- and NK-cell Neoplasms

NCT02232516Phase 2Active Not Recruiting

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

NCT02168140Phase 1Completed

CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

NCT06224842Phase 1UnknownPrimary

Clinical Study of Mitoxantrone Liposome and Azacitidine in the Treatment of R/R AITL

NCT01769222Phase 1Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

NCT04828174Phase 1Suspended

Anti-TRBC1 CAR-T Cell Therapy in Patients With TRBC1 Positive T Cell Malignancies

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