Key Insights

Highlights

Success Rate

57% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

8.8%

3 terminated out of 34 trials

Success Rate

57.1%

-29.4% vs benchmark

Late-Stage Pipeline

12%

4 trials in Phase 3/4

Results Transparency

50%

2 of 4 completed with results

Key Signals

2 with results57% success

Data Visualizations

Phase Distribution

23Total
Not Applicable (6)
Early P 1 (6)
P 1 (2)
P 2 (5)
P 3 (2)
P 4 (2)

Trial Status

Recruiting12
Unknown6
Not Yet Recruiting4
Completed4
Active Not Recruiting3
Terminated3

Trial Success Rate

57.1%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (34)

Showing 20 of 20 trials
NCT05376319Phase 2Terminated

PR3-AAV Resilient Remission or PRRR

NCT04316494Phase 4TerminatedPrimary

Hydroxychloroquine in ANCA Vasculitis Evaluation

NCT06548607Early Phase 1Recruiting

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

NCT06152172Phase 1Active Not Recruiting

CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101

NCT06549296Early Phase 1Suspended

Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune Diseases

NCT06548620Early Phase 1Withdrawn

A Study of RD06-04 in Patients With Active Autoimmune Diseases

NCT07301164Early Phase 1Not Yet Recruiting

Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases

NCT03906227Not ApplicableTerminatedPrimary

Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis

NCT07203404Early Phase 1Recruiting

A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.

NCT05630612Phase 2Active Not RecruitingPrimary

ETA and AT1 Antagonism in ANCA-vasculitis (SPARVASC)

NCT07077304Not Yet Recruiting

EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases

NCT07010250Not Yet RecruitingPrimary

Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis

NCT03698071Not ApplicableCompletedPrimary

Soluble CD95 Ligand Role in the Pathophysiology of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

NCT05946564Phase 3RecruitingPrimary

A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO Trial

NCT06685042Phase 1Recruiting

Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases

NCT04664465Recruiting

PRediction of DIverse Glucocorticoids ToxIcity OUtcomeS

NCT06794827RecruitingPrimary

Early-access Avacopan in Real-world ANCA-associated Vasculitis

NCT06508346RecruitingPrimary

Study of Therapeutic Efficacy of Anti-CD19 CAR-T Cells in Children With Refractory Refractory AAV

NCT04916704Active Not RecruitingPrimary

Subclinical Cytomegalovirus Reactivation in Acute ANCA-associated Vasculitis

NCT06462768Recruiting

Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis

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