Key Insights

Highlights

Success Rate

57% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

8.6%

3 terminated out of 35 trials

Success Rate

57.1%

-29.4% vs benchmark

Late-Stage Pipeline

11%

4 trials in Phase 3/4

Results Transparency

50%

2 of 4 completed with results

Key Signals

2 with results57% success

Data Visualizations

Phase Distribution

24Total
Not Applicable (6)
Early P 1 (7)
P 1 (2)
P 2 (5)
P 3 (2)
P 4 (2)

Trial Status

Recruiting12
Unknown6
Completed4
Active Not Recruiting4
Not Yet Recruiting3
Terminated3

Trial Success Rate

57.1%

Benchmark: 86.6%

Based on 4 completed trials

Clinical Trials (35)

Showing 20 of 20 trials
NCT07203404Early Phase 1Recruiting

A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.

NCT07596680Early Phase 1Not Yet Recruiting

CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune Diseases

NCT05946564Phase 3RecruitingPrimary

A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO Trial

NCT07010250RecruitingPrimary

Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis

NCT06508346WithdrawnPrimary

Study of Therapeutic Efficacy of Anti-CD19 CAR-T Cells in Children With Refractory Refractory AAV

NCT04664465Active Not Recruiting

PRediction Of DIverse Glucocorticoids toxIcity OUtcomeS

NCT07077304Recruiting

EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases

NCT05376319Phase 2Terminated

PR3-AAV Resilient Remission or PRRR

NCT04316494Phase 4TerminatedPrimary

Hydroxychloroquine in ANCA Vasculitis Evaluation

NCT06548607Early Phase 1Recruiting

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

NCT06152172Phase 1Active Not Recruiting

CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101

NCT06548620Early Phase 1Withdrawn

A Study of RD06-04 in Patients With Active Autoimmune Diseases

NCT06549296Early Phase 1Suspended

Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune Diseases

NCT07301164Early Phase 1Not Yet Recruiting

Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases

NCT03906227Not ApplicableTerminatedPrimary

Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis

NCT05630612Phase 2Active Not RecruitingPrimary

ETA and AT1 Antagonism in ANCA-vasculitis (SPARVASC)

NCT03698071Not ApplicableCompletedPrimary

Soluble CD95 Ligand Role in the Pathophysiology of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

NCT06685042Phase 1Recruiting

Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases

NCT06794827RecruitingPrimary

Early-access Avacopan in Real-world ANCA-associated Vasculitis

NCT04916704Active Not RecruitingPrimary

Subclinical Cytomegalovirus Reactivation in Acute ANCA-associated Vasculitis

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Research Network

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