Key Insights

Highlights

Success Rate

68% trial completion

Published Results

23 trials with published results (15%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.1%

19 terminated out of 157 trials

Success Rate

68.3%

-18.3% vs benchmark

Late-Stage Pipeline

5%

8 trials in Phase 3/4

Results Transparency

56%

23 of 41 completed with results

Key Signals

23 with results68% success19 terminated

Data Visualizations

Phase Distribution

137Total
Not Applicable (48)
Early P 1 (7)
P 1 (32)
P 2 (42)
P 3 (6)
P 4 (2)

Trial Status

Recruiting43
Completed41
Active Not Recruiting33
Terminated19
Withdrawn13
Not Yet Recruiting5

Trial Success Rate

68.3%

Benchmark: 86.6%

Based on 41 completed trials

Clinical Trials (157)

Showing 20 of 20 trials
NCT05564377Phase 2Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT03939481Active Not Recruiting

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

NCT02115282Phase 3Active Not RecruitingPrimary

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

NCT04379570Phase 3Active Not Recruiting

Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

NCT06058377Phase 3Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

NCT07460752Phase 2Recruiting

Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients

NCT05422794Phase 1RecruitingPrimary

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

NCT06179303Phase 2RecruitingPrimary

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

NCT04715958Phase 2Active Not RecruitingPrimary

SHAPE Neoadjuvant Chemotherapy Response

NCT06999798Phase 1Recruiting

An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 Trial

NCT01334021Phase 2Active Not Recruiting

Genetic Testing in Predicting Tumor Response in Patients With Stage I-III HER2 Negative Invasive Breast Cancer

NCT02453620Phase 1Active Not RecruitingPrimary

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

NCT04090567Phase 2Recruiting

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

NCT05710328Phase 2Active Not Recruiting

Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial

NCT04001829Phase 2Active Not Recruiting

Docetaxel or Paclitaxel in Reducing Chemotherapy-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

NCT04704661Phase 1Active Not Recruiting

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT05327608Not ApplicableRecruiting

Time Restricted Eating for the Improvement of Outcomes in Patients With Stage I-III Breast Cancer Receiving Chemotherapy Before Surgery

NCT06635980Phase 2Recruiting

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

NCT07594678Phase 2Not Yet Recruiting

Minoxidil With or Without Low-Level Red-Light Therapy for Improving Chemotherapy-Induced Alopecia in Breast Cancer Patients

NCT02849496Phase 2Active Not RecruitingPrimary

Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer

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