Key Insights

Highlights

Success Rate

75% trial completion

Published Results

19 trials with published results (13%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

8.6%

13 terminated out of 151 trials

Success Rate

74.5%

-12.0% vs benchmark

Late-Stage Pipeline

6%

9 trials in Phase 3/4

Results Transparency

50%

19 of 38 completed with results

Key Signals

19 with results75% success13 terminated

Data Visualizations

Phase Distribution

132Total
Not Applicable (45)
Early P 1 (7)
P 1 (31)
P 2 (40)
P 3 (8)
P 4 (1)

Trial Status

Recruiting49
Completed38
Active Not Recruiting31
Terminated13
Withdrawn12
Not Yet Recruiting6

Trial Success Rate

74.5%

Benchmark: 86.5%

Based on 38 completed trials

Clinical Trials (151)

Showing 20 of 20 trials
NCT05564377Phase 2Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT06058377Phase 3Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

NCT02918474Not ApplicableRecruiting

Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer

NCT06179303Phase 2RecruitingPrimary

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

NCT04678414Active Not Recruiting

Infertility Survey Among Reproductive Age Women With Gynecological and Breast Cancer

NCT07443943Phase 2Recruiting

A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial

NCT05673200Phase 1RecruitingPrimary

Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

NCT02453620Phase 1Active Not RecruitingPrimary

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

NCT05422794Phase 1RecruitingPrimary

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

NCT03939481Active Not Recruiting

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

NCT07137416Phase 1RecruitingPrimary

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

NCT04550494Phase 2RecruitingPrimary

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

NCT05372640Phase 1RecruitingPrimary

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

NCT04704661Phase 1Recruiting

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT04314401Active Not Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

NCT04491942Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

NCT04345913Phase 1Active Not RecruitingPrimary

Testing the Addition of Copanlisib to Eribulin in Metastatic Triple Negative Breast Cancer

NCT05568472Not ApplicableActive Not Recruiting

Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study

NCT05547347SuspendedPrimary

Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients With Locally Advanced Breast Cancer

NCT06401889Recruiting

Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy

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