Key Insights

Highlights

Success Rate

79% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

13.8%

4 terminated out of 29 trials

Success Rate

78.9%

-7.6% vs benchmark

Late-Stage Pipeline

14%

4 trials in Phase 3/4

Results Transparency

60%

9 of 15 completed with results

Key Signals

9 with results79% success

Data Visualizations

Phase Distribution

26Total
Not Applicable (2)
P 1 (15)
P 2 (5)
P 3 (4)

Trial Status

Completed15
Unknown6
Terminated4
Recruiting2
Withdrawn1
Active Not Recruiting1

Trial Success Rate

78.9%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (29)

Showing 20 of 20 trials
NCT03180502Phase 2Active Not Recruiting

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

NCT02800486Phase 2Recruiting

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

NCT04623931Phase 2Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

NCT01849952Terminated

Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas

NCT02026271Phase 1Completed

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma

NCT03043391Phase 1Completed

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

NCT01922076Phase 1Completed

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

NCT02168270Phase 1Terminated

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

NCT01721577Phase 1Terminated

Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas

NCT03072134Phase 1Completed

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

NCT05600491Phase 3UnknownPrimary

A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme

NCT00303849Phase 1CompletedPrimary

Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors

NCT01189266Phase 1Completed

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

NCT02015819Phase 1Completed

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

NCT00035373Terminated

Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols

NCT01470794Phase 1Completed

Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor

NCT01156584Phase 1Completed

A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma

NCT01985256Phase 1Completed

Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor

NCT01765088Phase 3UnknownPrimary

A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas

NCT02629757Phase 3UnknownPrimary

A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas

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