Key Insights

Highlights

Success Rate

82% trial completion

Published Results

43 trials with published results (39%)

Research Maturity

72 completed trials (65% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.5%

16 terminated out of 110 trials

Success Rate

81.8%

-4.7% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

60%

43 of 72 completed with results

Key Signals

43 with results82% success16 terminated

Data Visualizations

Phase Distribution

106Total
Not Applicable (8)
Early P 1 (3)
P 1 (58)
P 2 (37)

Trial Status

Completed72
Terminated16
Recruiting7
Active Not Recruiting6
Withdrawn4
Unknown4

Trial Success Rate

81.8%

Benchmark: 86.5%

Based on 72 completed trials

Clinical Trials (110)

Showing 20 of 20 trials
NCT05377827Phase 1Active Not Recruiting

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

NCT06508463Phase 1Recruiting

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

NCT07001384Phase 1Recruiting

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

NCT07388563Phase 1Recruiting

Azacitidine and Abatacept in Relapsed or Refractory T-Cell Lymphoma

NCT07467317Not Yet RecruitingPrimary

BV-CHP Real-life and Biological Evidences in Patients With sALCL

NCT03590574Phase 1Terminated

Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma

NCT04195633Phase 2Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

NCT07055477Phase 1Recruiting

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

NCT01199562Active Not Recruiting

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

NCT01787409Not ApplicableActive Not Recruiting

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

NCT05770037Phase 2Recruiting

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

NCT03598998Phase 1Active Not RecruitingPrimary

Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

NCT05290155Phase 1Completed

Anti-CD7 CAR-T Cell Therapy for Relapse and Refractory CD7 Positive T Cell Malignancies

NCT03443128Phase 2CompletedPrimary

Vinorelbine for Recurrent ALCL-2017

NCT03493451Phase 2Completed

Study of BGB-A317 in Participants With Relapsed or Refractory Mature T- and NK-cell Neoplasms

NCT01793233CompletedPrimary

Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas

NCT06494371Phase 1Recruiting

A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma

NCT02232516Phase 2Active Not Recruiting

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

NCT01588015Phase 1Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

NCT02168140Phase 1Completed

CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

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Research Network

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