Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

33.3%

5 terminated out of 15 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

7%

1 trials in Phase 3/4

Results Transparency

120%

6 of 5 completed with results

Key Signals

6 with results50% success

Data Visualizations

Phase Distribution

15Total
P 1 (9)
P 2 (5)
P 3 (1)

Trial Status

Completed5
Terminated5
Recruiting2
Withdrawn2
Active Not Recruiting1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (15)

Showing 15 of 15 trials
NCT01096368Phase 3CompletedPrimary

Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma

NCT05278208Phase 1Recruiting

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

NCT04978727Phase 1Active Not Recruiting

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

NCT03750513Phase 1RecruitingPrimary

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

NCT01295944Phase 2Completed

Carboplatin and Bevacizumab for Recurrent Ependymoma

NCT02722512Phase 1Terminated

Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine

NCT02101905Phase 1Completed

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

NCT04521946Phase 1WithdrawnPrimary

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

NCT03434262Phase 1Completed

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

NCT01721577Phase 1Terminated

Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas

NCT03727841Phase 2TerminatedPrimary

Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma

NCT01836549Phase 2Terminated

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

NCT01082926Phase 1Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

NCT01095094Phase 2Terminated

Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma

NCT00243490Phase 2Withdrawn

Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors

Showing all 15 trials

Research Network

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