Amyotrophic Lateral Sclerosis (ALS)
123
36
40
44
Key Insights
Highlights
Success Rate
92% trial completion (above average)
Published Results
15 trials with published results (12%)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
3.3%
4 terminated out of 123 trials
91.7%
+5.1% vs benchmark
10%
12 trials in Phase 3/4
34%
15 of 44 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 44 completed trials
Clinical Trials (123)
Study of COYA 302 for the Treatment of ALS
Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS
Lung Insufflation Capacity Training and Respiratory Function in Amyotrophic Lateral Sclerosis
Safety Study of XT-150 in Participants With ALS
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP 2 (PALADIN2)
PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS
First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)
Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis
Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS)
Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III
Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)
Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Serum Neurofilaments in the Diagnosis of Amyotrophic Lateral Sclerosis
HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial
HEALEY ALS Platform Trial - Regimen I NUZ-001
Personalized Antisense Oligonucleotide Therapy for a Participant With TARDBP ALS
Intestinal Microbiome Transplant in ALS
Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)
A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)