Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

15 trials with published results (12%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

3.3%

4 terminated out of 123 trials

Success Rate

91.7%

+5.1% vs benchmark

Late-Stage Pipeline

10%

12 trials in Phase 3/4

Results Transparency

34%

15 of 44 completed with results

Key Signals

15 with results92% success

Data Visualizations

Phase Distribution

98Total
Not Applicable (33)
Early P 1 (5)
P 1 (16)
P 2 (32)
P 3 (11)
P 4 (1)

Trial Status

Completed44
Recruiting36
Not Yet Recruiting15
Unknown8
Enrolling By Invitation7
Active Not Recruiting4

Trial Success Rate

91.7%

Benchmark: 86.6%

Based on 44 completed trials

Clinical Trials (123)

Showing 20 of 20 trials
NCT07161999Phase 2RecruitingPrimary

Study of COYA 302 for the Treatment of ALS

NCT07743268Phase 1Enrolling By InvitationPrimary

Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS

NCT07257302Not ApplicableRecruitingPrimary

Lung Insufflation Capacity Training and Respiratory Function in Amyotrophic Lateral Sclerosis

NCT06704347Phase 1Not Yet RecruitingPrimary

Safety Study of XT-150 in Participants With ALS

NCT07023835Phase 2RecruitingPrimary

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

NCT07726563Not ApplicableRecruitingPrimary

Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP 2 (PALADIN2)

NCT07142291Phase 2RecruitingPrimary

PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

NCT06351592Phase 1RecruitingPrimary

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

NCT01492686Phase 3CompletedPrimary

Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis

NCT00330681Phase 3CompletedPrimary

Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS)

NCT00415519Phase 3CompletedPrimary

Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III

NCT00424463Phase 3CompletedPrimary

Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT04577404Phase 3CompletedPrimary

Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)

NCT07706270Not Yet RecruitingPrimary

Serum Neurofilaments in the Diagnosis of Amyotrophic Lateral Sclerosis

NCT06719947Phase 2RecruitingPrimary

HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial

NCT07410806Phase 2Active Not RecruitingPrimary

HEALEY ALS Platform Trial - Regimen I NUZ-001

NCT07703462Phase 1Enrolling By InvitationPrimary

Personalized Antisense Oligonucleotide Therapy for a Participant With TARDBP ALS

NCT07017946Phase 1RecruitingPrimary

Intestinal Microbiome Transplant in ALS

NCT07521930Not ApplicableRecruiting

Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

NCT06643481Phase 2Active Not RecruitingPrimary

A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)

Scroll to load more

Research Network

Activity Timeline