Key Insights

Highlights

Success Rate

91% trial completion (above average)

Published Results

15 trials with published results (13%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

3.4%

4 terminated out of 116 trials

Success Rate

91.5%

+5.0% vs benchmark

Late-Stage Pipeline

10%

12 trials in Phase 3/4

Results Transparency

35%

15 of 43 completed with results

Key Signals

15 with results91% success

Data Visualizations

Phase Distribution

92Total
Not Applicable (30)
Early P 1 (5)
P 1 (13)
P 2 (32)
P 3 (11)
P 4 (1)

Trial Status

Completed43
Recruiting30
Not Yet Recruiting16
Unknown8
Enrolling By Invitation6
Terminated4

Trial Success Rate

91.5%

Benchmark: 86.5%

Based on 43 completed trials

Clinical Trials (116)

Showing 20 of 20 trials
NCT06877143Not ApplicableRecruitingPrimary

Hypercaloric PEG Nutrition in ALS to Sustain Energy Homeostasis

NCT07567664Not ApplicableEnrolling By Invitation

Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases

NCT07071935Phase 2Not Yet RecruitingPrimary

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

NCT07161999Phase 2RecruitingPrimary

Study of COYA 302 for the Treatment of ALS

NCT07521930Not ApplicableRecruiting

Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

NCT07017946Phase 1RecruitingPrimary

Intestinal Microbiome Transplant in ALS

NCT07142291Phase 2RecruitingPrimary

PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

NCT07454733Not ApplicableNot Yet RecruitingPrimary

Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?

NCT06351592Phase 1RecruitingPrimary

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

NCT07298486Not ApplicableEnrolling By InvitationPrimary

Impact of Robotic Glove Use on Quality of Life, Grip Strength and Fine Motor Control in ALS

NCT07410806Phase 2Enrolling By InvitationPrimary

HEALEY ALS Platform Trial - Regimen I NUZ-001

NCT07023835Phase 2Active Not RecruitingPrimary

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

NCT03233646Recruiting

Retinal Imaging in Neurodegenerative Disease

NCT07380204Not ApplicableRecruiting

Quantification of Hsp90 in the Human Brain

NCT07233148RecruitingPrimary

Healing ALS Registry Observational Study (HAROS)

NCT07369076Phase 1Not Yet RecruitingPrimary

A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis.

NCT00330681Phase 3CompletedPrimary

Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS)

NCT00424463Phase 3CompletedPrimary

Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT00415519Phase 3CompletedPrimary

Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III

NCT01492686Phase 3CompletedPrimary

Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis

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