Key Insights

Highlights

Success Rate

87% trial completion (above average)

Published Results

20 trials with published results (15%)

Research Maturity

60 completed trials (45% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

6.8%

9 terminated out of 132 trials

Success Rate

87.0%

+0.5% vs benchmark

Late-Stage Pipeline

8%

10 trials in Phase 3/4

Results Transparency

33%

20 of 60 completed with results

Key Signals

20 with results87% success

Data Visualizations

Phase Distribution

84Total
Not Applicable (24)
Early P 1 (2)
P 1 (23)
P 2 (25)
P 3 (10)

Trial Status

Completed60
Recruiting29
Unknown15
Terminated9
Withdrawn9
Active Not Recruiting5

Trial Success Rate

87.0%

Benchmark: 86.5%

Based on 60 completed trials

Clinical Trials (132)

Showing 20 of 20 trials
NCT05250973Phase 2Active Not RecruitingPrimary

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

NCT06414746Completed

Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia

NCT04636684Not ApplicableRecruitingPrimary

Prevalence and Significance of ATTR Aortic Valve Amyloidosis in Degenerative Aortic Stenosis

NCT06974877Phase 1Recruiting

Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load

NCT07285044Phase 2RecruitingPrimary

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT06563895Phase 3RecruitingPrimary

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

NCT05145816Phase 1Recruiting

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

NCT03584022Not ApplicableActive Not Recruiting

Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial

NCT06251778RecruitingPrimary

NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis

NCT06672237Phase 3Recruiting

A Phase 3 Study of NTLA-2001 in ATTRv-PN

NCT05758493Phase 2RecruitingPrimary

Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis

NCT07494942Not ApplicableNot Yet RecruitingPrimary

Impact of a Cardiac Rehabilitation Program on Patients With Cardiac Amyloidosis

NCT07081646Phase 1Recruiting

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

NCT07224672Phase 2Not Yet RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants With Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis

NCT03019029Phase 1CompletedPrimary

Diagnostic Utility of F-18 Florbetapir PET/MR in Peripheral Nerve Amyloidosis

NCT03431896CompletedPrimary

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

NCT07172243RecruitingPrimary

BE.Amycon Biobank & Data Registry UZ Leuven

NCT03702829Phase 2TerminatedPrimary

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

NCT04661800Not ApplicableCompletedPrimary

Study of Olfactory Disorders in Patients With Cardiac Amyloidosis

NCT07388602Phase 3RecruitingPrimary

A Study to Evaluate the Safety and Efficacy of SCTC21C in Combination With Bortezomib, Cyclophosphamide, and Dexamethasone in Patients With Newly Diagnosed Systemic Light-Chain Amyloidosis (NDSLCA)

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