Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

0.0%

0 terminated out of 22 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

18%

4 trials in Phase 3/4

Results Transparency

33%

1 of 3 completed with results

Key Signals

1 with results100% success

Data Visualizations

Phase Distribution

12Total
Not Applicable (6)
P 1 (1)
P 2 (1)
P 3 (3)
P 4 (1)

Trial Status

Recruiting7
Unknown5
Not Yet Recruiting4
Active Not Recruiting3
Completed3

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT06261216CompletedPrimary

Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

NCT06563895Phase 3Recruiting

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

NCT03431896Completed

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

NCT07382128Recruiting

Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes

NCT05103943Not ApplicableActive Not RecruitingPrimary

Amyloidosis TTR Flow Reserve Evaluation

NCT07240844Phase 4Not Yet RecruitingPrimary

Enavogliflozin for the Management of Patients With Amyloid CardiomyopaThy

NCT07116473Phase 3Not Yet Recruiting

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

NCT06634108Phase 1RecruitingPrimary

Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy

NCT04776824RecruitingPrimary

Swiss Cardiac Amyloidosis REgistry (Swiss-CARE)

NCT05797857Not ApplicableRecruitingPrimary

Exercise Training in Transthyretin Cardiac Amyloidosis

NCT03536767Phase 2Active Not RecruitingPrimary

Open-Label Study of AG10 in Patients with Cardiomyopathy

NCT05795400Not ApplicableActive Not Recruiting

Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy

NCT06748261Not Yet Recruiting

AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA

NCT06499064Not ApplicableNot Yet Recruiting

EOSS-ATTR Study (eHealth Based Operative Support System in ATTR-CM)

NCT03860935Phase 3Completed

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

NCT06328075RecruitingPrimary

Artificial Intelligence to Assist the Echocardiographic Identification of Transthyretin Cardiac Amyloidosis

NCT05452850UnknownPrimary

Longitudinal Changes in Left and Right Ventricular Global Strain After Chemotherapy in Cardiac Light Chain Amyloidosis

NCT05448716Unknown

Left Atrial Strain and Supraventricular Arrhythmia Burden in Cardiac Light Chain Amyloidosis Following Chemotherapy

NCT06048601Not ApplicableUnknown

18F-florbetaben PET-CT to Non-invasively Diagnose Cardiac AL Amyloidosis

NCT05699044UnknownPrimary

Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker Implantation

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Research Network

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