Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

6.7%

1 terminated out of 15 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

1 of 2 completed with results

Key Signals

1 with results67% success

Data Visualizations

Phase Distribution

10Total
Not Applicable (2)
P 1 (2)
P 2 (6)

Trial Status

Recruiting7
Active Not Recruiting2
Unknown2
Completed2
Terminated1
Withdrawn1

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (15)

Showing 15 of 15 trials
NCT05713006Phase 1Recruiting

Alectinib Pharmacokinetic in Patients With NSCLC

NCT03042221Recruiting

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

NCT05370469Not ApplicableActive Not Recruiting

Real-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies

NCT05200481Phase 2Active Not Recruiting

Study of Safety and Efficacy of Brigatinib Plus Chemotherapy or Brigatinib Only in Advanced ALK-Positive Lung Cancer (MASTERPROTOCOL ALK)

NCT03049618Phase 2CompletedPrimary

Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475

NCT04322890Phase 2Recruiting

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation

NCT06234579RecruitingPrimary

Longitudinal Assessment of Genomic Alterations and Clonal Evolution in ALK-positive NSCLC (Galileo Project)

NCT05266846Phase 2RecruitingPrimary

Pembrolizumab Plus Bevacizumab and Chemotherapy for ALK-rearranged NSCLC With Persistent 5'ALK

NCT06378892Phase 2Recruiting

A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib

NCT05724004Not ApplicableRecruiting

Alectinib Followed by Concomitant Consolidation Radiation Therapy in Advanced NSCLC With ALK-rearrangement (A-SAB)

NCT05534854Unknown

Frequency, Clinical Phenotype and Genetic Analysis of Heritable Kidney Cancer Syndromes

NCT01700582Completed

French National Observatory of the Patients With Non-small Cell Lung (NSCLC) and Molecular Testings

NCT04849273Phase 1Terminated

A Study of TPX-0131, a Novel Oral ALK Tyrosine Kinase Inhibitor, in Patients With ALK+ Advanced or Metastatic NSCLC

NCT03868423Phase 2Withdrawn

Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers

NCT04708639Unknown

Monitoring Alectinib Treatment by Detection of ALK Translocations in Serial Blood Samples From Non-Small Cell Lung Cancer Patients

Showing all 15 trials

Research Network

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