Key Insights

Highlights

Success Rate

60% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 55/100

Termination Rate

40.0%

4 terminated out of 10 trials

Success Rate

60.0%

-26.5% vs benchmark

Late-Stage Pipeline

90%

9 trials in Phase 3/4

Results Transparency

83%

5 of 6 completed with results

Key Signals

5 with results60% success

Data Visualizations

Phase Distribution

10Total
P 2 (1)
P 3 (9)

Trial Status

Completed6
Terminated4

Trial Success Rate

60.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (10)

Showing 10 of 10 trials
NCT06736509Phase 3TerminatedPrimary

An Open-Label Study to Assess the Long-term Safety of AXS-05 in Subjects With Dementia of the Alzheimer's Type, ADVANCE-2 and ACCORD-2 Extension Study

NCT04947553Phase 3CompletedPrimary

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

NCT05557409Phase 3CompletedPrimary

A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation

NCT02446132Phase 3TerminatedPrimary

Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

NCT04408755Phase 3TerminatedPrimary

Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

NCT04464564Phase 3TerminatedPrimary

Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

NCT03393520Phase 3CompletedPrimary

Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

NCT04797715Phase 3CompletedPrimary

Assessing Clinical Outcomes in Alzheimer's Disease Agitation

NCT03226522Phase 2CompletedPrimary

Addressing Dementia Via Agitation-Centered Evaluation

NCT02442765Phase 3CompletedPrimary

Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Showing all 10 trials

Research Network

Activity Timeline