Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 87/100

Termination Rate

20.8%

10 terminated out of 48 trials

Success Rate

70.6%

-15.9% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

21%

5 of 24 completed with results

Key Signals

5 with results71% success

Data Visualizations

Phase Distribution

48Total
P 1 (45)
P 2 (3)

Trial Status

Completed24
Terminated10
Recruiting8
Unknown3
Active Not Recruiting2
Withdrawn1

Trial Success Rate

70.6%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (48)

Showing 20 of 20 trials
NCT06599502Phase 1TerminatedPrimary

A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation

NCT05514132Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Safety and Pharmacokinetics of Ceralasertib in Combination With Durvalumab in Chinese Patients With Advanced Solid Tumours

NCT02617277Phase 1CompletedPrimary

Safety, Tolerability and Pharmacokinetics of AZD1775 (Adavosertib) Plus MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumours

NCT05647122Phase 1RecruitingPrimary

First in Human Study of AZD9592 in Solid Tumors

NCT05701527Phase 1RecruitingPrimary

A Study of EBC-129 in Advanced Solid Tumours

NCT07348211Phase 1RecruitingPrimary

First in Human Study of SIM0610 in Solid Tumors

NCT06929260Phase 1TerminatedPrimary

A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug Z

NCT03746431Phase 1TerminatedPrimary

A Phase 1 Study of [225Ac]-FPI-1434 Injection

NCT05508334Phase 1CompletedPrimary

A Study to Assess the Safety and Tolerability of RC88 for Patients With Advanced Solid Tumours

NCT06815575Phase 1Recruiting

A Safety and Pharmacokinetics Study of RC220 Combined With Doxorubicin in Adult Participants With Solid Tumours.

NCT06868199Phase 1RecruitingPrimary

A Study of LM-168 as a Single Agent or in Combination With Toripalimab in Subjects With Advanced Solid Tumours

NCT04564027Phase 2CompletedPrimary

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

NCT04946968Phase 2Active Not RecruitingPrimary

Phase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or Other Novel Emerging Biomarkers

NCT06927349Phase 1RecruitingPrimary

A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BA1301 in Advanced Solid Tumors.

NCT04907851Phase 2CompletedPrimary

A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2)

NCT03518606Phase 1CompletedPrimary

Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours

NCT04504669Phase 1Completed

First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours

NCT03486730Phase 1CompletedPrimary

BT1718 in Patients with Advanced Solid Tumours.

NCT02389842Phase 1CompletedPrimary

PIPA: Combination of PI3 Kinase Inhibitors and PAlbociclib

NCT04434482Phase 1CompletedPrimary

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

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