Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

4.8%

1 terminated out of 21 trials

Success Rate

87.5%

+0.9% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 7 completed with results

Key Signals

88% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (1)
P 1 (18)

Trial Status

Completed7
Recruiting5
Active Not Recruiting4
Not Yet Recruiting4
Terminated1

Trial Success Rate

87.5%

Benchmark: 86.6%

Based on 7 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT07689812Not ApplicableNot Yet Recruiting

A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

NCT07678593Phase 1Not Yet RecruitingPrimary

A Study of GFH276 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors and Pancreatic Ductal Adenocarcinoma (PDAC) Harboring RAS Mutation

NCT07327489Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

NCT06898450Phase 1RecruitingPrimary

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

NCT07514975Phase 1Not Yet RecruitingPrimary

First-In-Human Study of KHN922 for Injection

NCT07190469Phase 1Recruiting

PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer

NCT06607939Phase 1RecruitingPrimary

ORB-021 In Patients With Advanced Solid Tumors

NCT02988960Phase 1Active Not RecruitingPrimary

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

NCT07259590Phase 1RecruitingPrimary

A Study of GFH375 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors Harboring KRAS G12D Mutation

NCT04417465Phase 1CompletedPrimary

First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors

NCT02099058Phase 1Active Not RecruitingPrimary

A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors

NCT07118709Phase 1Not Yet RecruitingPrimary

A Study of KC1086 in Patients With Advanced Solid Tumors

NCT04721015Phase 1Active Not RecruitingPrimary

Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors

NCT07035470CompletedPrimary

Biological Age Predicts 90-Day Mortality in Advanced Cancer

NCT03821935Phase 1Active Not RecruitingPrimary

Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors

NCT04196283Phase 1CompletedPrimary

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

NCT03071757Phase 1CompletedPrimary

A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT03234712Phase 1CompletedPrimary

A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)

NCT02955251Phase 1CompletedPrimary

A Study of ABBV-428, an Immunotherapy, in Subjects With Advanced Solid Tumors

NCT03311477Phase 1CompletedPrimary

A Study to Evaluate the Safety and Pharmacokinetics ABBV-399 in Japanese Participants With Solid Tumors

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