Key Insights

Highlights

Success Rate

58% trial completion

Published Results

11 trials with published results (15%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 87/100

Termination Rate

20.8%

15 terminated out of 72 trials

Success Rate

58.3%

-28.2% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

52%

11 of 21 completed with results

Key Signals

11 with results58% success15 terminated

Data Visualizations

Phase Distribution

72Total
Early P 1 (1)
P 1 (70)
P 2 (1)

Trial Status

Completed21
Recruiting17
Terminated15
Active Not Recruiting12
Unknown3
Not Yet Recruiting3

Trial Success Rate

58.3%

Benchmark: 86.6%

Based on 21 completed trials

Clinical Trials (72)

Showing 20 of 20 trials
NCT07705334Phase 1RecruitingPrimary

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

NCT05538130Phase 1Recruiting

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

NCT06781983Phase 1Active Not RecruitingPrimary

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

NCT06752681Phase 1RecruitingPrimary

To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With Locally Advanced or Metastatic Solid Tumors

NCT07702955Phase 1Not Yet RecruitingPrimary

Phase I Study of Single-Agent KGX105 in Patients With Advanced or Metastatic Solid Tumors

NCT07205718Phase 1RecruitingPrimary

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

NCT05594043Phase 1CompletedPrimary

A Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001)

NCT05787587Phase 1Active Not RecruitingPrimary

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

NCT04866134Phase 1Active Not RecruitingPrimary

A Study of ERAS-007 as Monotherapy or in Combination With ERAS-601 in Patients With Advanced or Metastatic Solid Tumors

NCT05017012Phase 1CompletedPrimary

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

NCT06248411Phase 1RecruitingPrimary

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

NCT04843709Phase 1CompletedPrimary

A Study of MRG004A in Patients With Tissue Factor Positive Advanced or Metastatic Solid Tumors

NCT06074497Phase 1Active Not RecruitingPrimary

This is an Open Label, Two-part, Multicenter, Phase I Trial to Investigate the Safety, Tolerability, and PK of KGX101 Monotherapy and Combination Therapy With Envafolimab in Patients With Advanced or Metastatic Solid Tumors.

NCT07260305Phase 1RecruitingPrimary

A Phase I Study to Investigate the Safety and Tolerability of KGX101 Monotherapy and Combination Therapy With Envafolimab in Advanced or Metastatic Solid Tumor Patients

NCT05848466Phase 1CompletedPrimary

Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients

NCT06395519Phase 1RecruitingPrimary

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

NCT04670679Phase 1Active Not RecruitingPrimary

A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors

NCT06234397Phase 1RecruitingPrimary

Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

NCT05907304Phase 1Active Not RecruitingPrimary

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

NCT05753722Phase 1RecruitingPrimary

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

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Research Network

Activity Timeline