Key Insights

Highlights

Success Rate

60% trial completion

Published Results

12 trials with published results (17%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 87/100

Termination Rate

22.2%

16 terminated out of 72 trials

Success Rate

60.0%

-26.6% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

12 of 24 completed with results

Key Signals

12 with results60% success16 terminated

Data Visualizations

Phase Distribution

72Total
Early P 1 (1)
P 1 (70)
P 2 (1)

Trial Status

Completed24
Terminated16
Recruiting14
Active Not Recruiting11
Unknown3
Not Yet Recruiting3

Trial Success Rate

60.0%

Benchmark: 86.6%

Based on 24 completed trials

Clinical Trials (72)

Showing 20 of 20 trials
NCT05753722Phase 1CompletedPrimary

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

NCT06234397Phase 1RecruitingPrimary

Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

NCT07205718Phase 1RecruitingPrimary

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

NCT07705334Phase 1RecruitingPrimary

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

NCT04670679Phase 1CompletedPrimary

A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors

NCT04866134Phase 1CompletedPrimary

A Study of ERAS-007 as Monotherapy or in Combination With ERAS-601 in Patients With Advanced or Metastatic Solid Tumors

NCT03155061Phase 1Active Not RecruitingPrimary

Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors

NCT05538130Phase 1Active Not Recruiting

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

NCT06774963Phase 1Recruiting

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

NCT02220049Phase 1CompletedPrimary

Dose Escalation of Velcade Daily Dose in Patients With Solid Tumors

NCT05572684Phase 1TerminatedPrimary

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

NCT05598151Phase 1Active Not RecruitingPrimary

Dose Escalation and Expansion Study of HM97662 in Advanced or Metastatic Solid Tumors

NCT05382325Phase 1Active Not RecruitingPrimary

A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001)

NCT06781983Phase 1Active Not RecruitingPrimary

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

NCT06752681Phase 1RecruitingPrimary

To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With Locally Advanced or Metastatic Solid Tumors

NCT07702955Phase 1Not Yet RecruitingPrimary

Phase I Study of Single-Agent KGX105 in Patients With Advanced or Metastatic Solid Tumors

NCT05594043Phase 1CompletedPrimary

A Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001)

NCT05787587Phase 1Active Not RecruitingPrimary

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

NCT05017012Phase 1CompletedPrimary

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

NCT06248411Phase 1RecruitingPrimary

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

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