Key Insights

Highlights

Success Rate

56% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 87/100

Termination Rate

21.4%

15 terminated out of 70 trials

Success Rate

55.9%

-30.6% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

53%

10 of 19 completed with results

Key Signals

10 with results56% success15 terminated

Data Visualizations

Phase Distribution

70Total
Early P 1 (1)
P 1 (68)
P 2 (1)

Trial Status

Completed19
Recruiting18
Terminated15
Active Not Recruiting11
Unknown4
Not Yet Recruiting2

Trial Success Rate

55.9%

Benchmark: 86.5%

Based on 19 completed trials

Clinical Trials (70)

Showing 20 of 20 trials
NCT05538130Phase 1Recruiting

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

NCT06074497Phase 1Active Not RecruitingPrimary

This is an Open Label, Two-part, Multicenter, Phase I Trial to Investigate the Safety, Tolerability, and PK of KGX101 Monotherapy and Combination Therapy With Envafolimab in Patients With Advanced or Metastatic Solid Tumors.

NCT07260305Phase 1RecruitingPrimary

A Phase I Study to Investigate the Safety and Tolerability of KGX101 Monotherapy and Combination Therapy With Envafolimab in Advanced or Metastatic Solid Tumor Patients

NCT07205718Phase 1RecruitingPrimary

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

NCT05848466Phase 1CompletedPrimary

Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients

NCT06395519Phase 1RecruitingPrimary

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

NCT05017012Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

NCT04670679Phase 1Active Not RecruitingPrimary

A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors

NCT06248411Phase 1RecruitingPrimary

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

NCT06234397Phase 1RecruitingPrimary

Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

NCT05907304Phase 1Active Not RecruitingPrimary

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

NCT05753722Phase 1RecruitingPrimary

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

NCT06939283Phase 1Active Not RecruitingPrimary

A Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Lymphoma

NCT05787587Phase 1RecruitingPrimary

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

NCT06781983Phase 1RecruitingPrimary

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

NCT05678998Phase 1CompletedPrimary

WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma

NCT05957081Phase 1RecruitingPrimary

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309

NCT06724016Phase 1RecruitingPrimary

Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors

NCT06774963Phase 1Recruiting

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

NCT04381650Phase 1CompletedPrimary

A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors

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