Key Insights

Highlights

Success Rate

77% trial completion

Published Results

18 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.8%

12 terminated out of 81 trials

Success Rate

76.9%

-9.6% vs benchmark

Late-Stage Pipeline

5%

4 trials in Phase 3/4

Results Transparency

45%

18 of 40 completed with results

Key Signals

18 with results77% success12 terminated

Data Visualizations

Phase Distribution

80Total
P 1 (73)
P 2 (3)
P 3 (4)

Trial Status

Completed40
Terminated12
Unknown9
Recruiting8
Active Not Recruiting5
Not Yet Recruiting4

Trial Success Rate

76.9%

Benchmark: 86.5%

Based on 40 completed trials

Clinical Trials (81)

Showing 20 of 20 trials
NCT04181788Phase 1Active Not RecruitingPrimary

Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies

NCT04164199Phase 3Active Not RecruitingPrimary

Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With Advanced Malignancies

NCT05059522Phase 3Active Not RecruitingPrimary

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

NCT07340190Phase 1Not Yet RecruitingPrimary

A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies

NCT05891171Phase 1Active Not Recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT07504263Phase 1Not Yet RecruitingPrimary

Phase 1/2a Study of RP-001 in Participants With Advanced Malignancies

NCT05351697Phase 1TerminatedPrimary

Clinical Study of BR105 Injection

NCT07426757Phase 1Not Yet RecruitingPrimary

An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancers

NCT04752826Phase 1RecruitingPrimary

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

NCT03233139Phase 1Active Not RecruitingPrimary

Safety and Pharmacokinetics of Cemiplimab Anti-programmed Death-ligand 1 (Anti-PD-1) and Other Agents in Japanese Adult Patients With Advanced Malignancies

NCT06038058Phase 1RecruitingPrimary

A Study of BRY812 for Injection Alone in Subjects With Advanced Malignancies

NCT06937957Phase 1RecruitingPrimary

A Study of BR111 in Patients With Advanced Malignancies

NCT05577182Phase 1CompletedPrimary

Study of INCA32459 a LAG-3 and PD-1 Bispecific Antibody in Participants With Select Advanced Malignancies

NCT02959437Phase 1Terminated

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

NCT02923349Phase 1CompletedPrimary

A Phase 1/2, Open-Label, Dose-Escalation, Safety Study of INCAGN01949 in Subjects With Advanced or Metastatic Solid Tumors

NCT03126110Phase 1CompletedPrimary

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies

NCT04837196Phase 1CompletedPrimary

Study of ASP7517 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors Expressing WT1 Antigen

NCT05391022Phase 1CompletedPrimary

Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies

NCT06401356Phase 3Recruiting

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

NCT05987605Phase 1TerminatedPrimary

Phase I/II Clinical Study of 1A46 Drug Substance

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