Key Insights

Highlights

Success Rate

76% trial completion

Published Results

38 trials with published results (49%)

Research Maturity

56 completed trials (72% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

23.1%

18 terminated out of 78 trials

Success Rate

75.7%

-10.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

68%

38 of 56 completed with results

Key Signals

38 with results76% success18 terminated

Data Visualizations

Phase Distribution

78Total
Not Applicable (5)
Early P 1 (2)
P 1 (45)
P 2 (26)

Trial Status

Completed56
Terminated18
Withdrawn3
Active Not Recruiting1

Trial Success Rate

75.7%

Benchmark: 86.5%

Based on 56 completed trials

Clinical Trials (78)

Showing 20 of 20 trials
NCT00268385Phase 1Active Not Recruiting

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

NCT01165632Early Phase 1Completed

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

NCT02186509Phase 1Completed

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

NCT01894061Phase 2Completed

NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma

NCT00662506Phase 1Completed

Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

NCT04657315Phase 1Completed

Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients

NCT01730950Phase 2Completed

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

NCT00731731Phase 1Completed

Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT01062425Phase 2Completed

Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

NCT02015819Phase 1Completed

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

NCT01051557Phase 1Completed

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

NCT00052208Phase 1Completed

Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme

NCT01806675Phase 1Completed

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

NCT00423735Phase 2Completed

Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

NCT02337426Phase 1Completed

Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT00902577Phase 2Completed

MRI and PET/FMISO In Assessing Tumor Hypoxia in Patients With Newly Diagnosed Glioblastoma Multiforme

NCT01977677Phase 1Completed

Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

NCT00329719Phase 1Completed

Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma

NCT00433381Phase 2Completed

Bevacizumab and Irinotecan or Temozolomide in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme or Gliosarcoma

NCT01103375Phase 1Terminated

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

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