Key Insights

Highlights

Success Rate

73% trial completion

Published Results

36 trials with published results (49%)

Research Maturity

52 completed trials (70% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

25.7%

19 terminated out of 74 trials

Success Rate

73.2%

-13.3% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

69%

36 of 52 completed with results

Key Signals

36 with results73% success19 terminated

Data Visualizations

Phase Distribution

74Total
Not Applicable (5)
Early P 1 (2)
P 1 (42)
P 2 (25)

Trial Status

Completed52
Terminated19
Withdrawn2
Active Not Recruiting1

Trial Success Rate

73.2%

Benchmark: 86.5%

Based on 52 completed trials

Clinical Trials (74)

Showing 20 of 20 trials
NCT00268385Phase 1Active Not Recruiting

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

NCT01165632Early Phase 1Completed

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

NCT02186509Phase 1Completed

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

NCT01894061Phase 2CompletedPrimary

NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma

NCT00662506Phase 1CompletedPrimary

Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

NCT01730950Phase 2CompletedPrimary

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

NCT00731731Phase 1CompletedPrimary

Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT02015819Phase 1Completed

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

NCT01051557Phase 1Completed

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

NCT00052208Phase 1CompletedPrimary

Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme

NCT01478321Phase 2Terminated

Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas

NCT01806675Phase 1CompletedPrimary

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

NCT00423735Phase 2CompletedPrimary

Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

NCT02337426Phase 1Completed

Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT00902577Phase 2CompletedPrimary

MRI and PET/FMISO In Assessing Tumor Hypoxia in Patients With Newly Diagnosed Glioblastoma Multiforme

NCT01977677Phase 1Completed

Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

NCT01103375Phase 1Terminated

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

NCT01575275Phase 2TerminatedPrimary

Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme

NCT01234805Not ApplicableTerminated

Yoga Therapy in Treating Patients With Malignant Brain Tumors

NCT00335764Phase 1CompletedPrimary

Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

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