Key Insights

Highlights

Success Rate

70% trial completion

Published Results

27 trials with published results (47%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

29.3%

17 terminated out of 58 trials

Success Rate

69.6%

-16.9% vs benchmark

Late-Stage Pipeline

5%

3 trials in Phase 3/4

Results Transparency

69%

27 of 39 completed with results

Key Signals

27 with results70% success17 terminated

Data Visualizations

Phase Distribution

58Total
Not Applicable (3)
Early P 1 (1)
P 1 (25)
P 2 (26)
P 3 (3)

Trial Status

Completed39
Terminated17
Unknown1
Withdrawn1

Trial Success Rate

69.6%

Benchmark: 86.5%

Based on 39 completed trials

Clinical Trials (58)

Showing 20 of 20 trials
NCT01822015Early Phase 1Completed

Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02085408Phase 3Completed

Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT01555268Phase 1Completed

Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia

NCT01550185Phase 1Terminated

Eltrombopag Olamine in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT00352365Phase 2Completed

Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia

NCT02071901Phase 2Unknown

Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

NCT02144675Phase 2Completed

Choline Magnesium Trisalicylate and Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia

NCT02105116Not ApplicableTerminated

AML Therapy With Irradiated Allogeneic Cells

NCT01235572Phase 2Completed

Early Discharge and Outpatients Care in Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia Previously Treated With Intensive Chemotherapy

NCT01839240Phase 1Completed

Azacitidine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With High-Risk Acute Myeloid Leukemia

NCT00045435Phase 2Completed

Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission

NCT00895934Phase 1Completed

Vorinostat, Azacitidine, and Gemtuzumab Ozogamicin for Older Patients With Relapsed or Refractory AML

NCT02030405Phase 2Terminated

Ixazomib (MLN9708) in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT01031368Phase 1Completed

Clofarabine, Cytarabine, and Filgrastim Followed by Infusion of Non-HLA Matched Ex Vivo Expanded Cord Blood Progenitors in Treating Patients With Acute Myeloid Leukemia

NCT01849276Phase 1Terminated

Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

NCT01093586Phase 2Completed

Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

NCT01904643Phase 1Terminated

Lenalidomide and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT01253447Phase 2Completed

AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT00795002Phase 2Completed

Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT01872819Not ApplicableCompleted

Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay

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