Key Insights

Highlights

Success Rate

71% trial completion

Published Results

27 trials with published results (47%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

27.6%

16 terminated out of 58 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

5%

3 trials in Phase 3/4

Results Transparency

68%

27 of 40 completed with results

Key Signals

27 with results71% success16 terminated

Data Visualizations

Phase Distribution

58Total
Not Applicable (3)
Early P 1 (1)
P 1 (25)
P 2 (26)
P 3 (3)

Trial Status

Completed40
Terminated16
Unknown1
Withdrawn1

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 40 completed trials

Clinical Trials (58)

Showing 20 of 20 trials
NCT01822015Early Phase 1CompletedPrimary

Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02085408Phase 3Completed

Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT01555268Phase 1CompletedPrimary

Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia

NCT01550185Phase 1Terminated

Eltrombopag Olamine in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT00352365Phase 2Completed

Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia

NCT02071901Phase 2Unknown

Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

NCT02105116Not ApplicableTerminatedPrimary

AML Therapy With Irradiated Allogeneic Cells

NCT02144675Phase 2CompletedPrimary

Choline Magnesium Trisalicylate and Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia

NCT01235572Phase 2CompletedPrimary

Early Discharge and Outpatients Care in Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia Previously Treated With Intensive Chemotherapy

NCT01839240Phase 1CompletedPrimary

Azacitidine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With High-Risk Acute Myeloid Leukemia

NCT00045435Phase 2Completed

Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission

NCT00895934Phase 1CompletedPrimary

Vorinostat, Azacitidine, and Gemtuzumab Ozogamicin for Older Patients With Relapsed or Refractory AML

NCT02030405Phase 2TerminatedPrimary

Ixazomib (MLN9708) in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT01031368Phase 1CompletedPrimary

Clofarabine, Cytarabine, and Filgrastim Followed by Infusion of Non-HLA Matched Ex Vivo Expanded Cord Blood Progenitors in Treating Patients With Acute Myeloid Leukemia

NCT01849276Phase 1TerminatedPrimary

Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

NCT01093586Phase 2Completed

Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

NCT02019069Phase 2Completed

CPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT01904643Phase 1TerminatedPrimary

Lenalidomide and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT01253447Phase 2CompletedPrimary

AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT00795002Phase 2Completed

Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

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