Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

7.4%

2 terminated out of 27 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

11%

3 trials in Phase 3/4

Results Transparency

20%

1 of 5 completed with results

Key Signals

1 with results71% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (2)
Early P 1 (1)
P 1 (8)
P 2 (4)
P 3 (3)

Trial Status

Recruiting8
Completed5
Unknown5
Withdrawn3
Terminated2
Not Yet Recruiting2

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (27)

Showing 20 of 20 trials
NCT03665675Early Phase 1Recruiting

Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT

NCT05664126Phase 2Recruiting

Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus Infections After Hematopoietic Cell Transplantation

NCT07358910Recruiting

Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective

NCT07225972Phase 3Not Yet Recruiting

Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone

NCT06909110Phase 1RecruitingPrimary

Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised Immunity

NCT03266627Phase 2RecruitingPrimary

Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

NCT06926894Phase 1Recruiting

R-MVST Cells for Treatment of Viral Infections in Children and Young Adults

NCT01945814Phase 1Completed

Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)

NCT06027879Phase 1Enrolling By InvitationPrimary

Anti-viral T-cell Therapy by Gamma Capture

NCT05183490Phase 1Recruiting

R-MVST Cells for Treatment of Viral Infections

NCT04364178Phase 1Active Not RecruitingPrimary

Viral Specific T-Lymphocytes to Treat Adenovirus or CMV

NCT06392451Not ApplicableNot Yet Recruiting

LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in Australia

NCT06299813Phase 3RecruitingPrimary

Effectiveness of a Single Dose of Betamethasone in Children With Symptomatic Adenovirus Infection

NCT01431326CompletedPrimary

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

NCT02596997UnknownPrimary

Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease

NCT01535885Phase 1Completed

Using Multi-virus Cytotoxic T-cells Following T-Cell Depleted Allogeneic HPCT for Prophylaxis Against EBV, ADV, and CMV

NCT03532035Phase 2WithdrawnPrimary

Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia

NCT03339401Phase 2TerminatedPrimary

The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation

NCT04056546CompletedPrimary

Interest of Rapid Typing in Adenovirus Infections.

NCT03325517UnknownPrimary

Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics

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