Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

17.4%

4 terminated out of 23 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

9%

2 trials in Phase 3/4

Results Transparency

50%

4 of 8 completed with results

Key Signals

4 with results67% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (3)
P 1 (6)
P 2 (8)
P 3 (2)

Trial Status

Completed8
Unknown7
Terminated4
Recruiting2
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT03805789Phase 2CompletedPrimary

The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant

NCT05123040Phase 1TerminatedPrimary

Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids

NCT05236062Not ApplicableRecruiting

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

NCT05149365Phase 3CompletedPrimary

Sitagliptin for Prevention of aGVHD After Alternative Donor Transplation

NCT03847844Phase 1CompletedPrimary

UCMSCs as Front-line Approach of Treatment for Patients With aGVHD

NCT05263999Phase 3Terminated

A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR)

NCT03763318Phase 1CompletedPrimary

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD

NCT04291261Phase 2Active Not RecruitingPrimary

Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease

NCT03148743RecruitingPrimary

FMT in Gut aGVHD Treated

NCT04014790Phase 2Completed

RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation

NCT05121142Phase 1CompletedPrimary

Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease

NCT03557749Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

NCT04883918Phase 2Not Yet RecruitingPrimary

ASC930 in Patients With Steroid-Refractory Acute Graft Versus Host Disease (SR-aGVHD)

NCT04686929Phase 1Unknown

Abatacept s.c. for aGVHD Prevention in Haplo-HCT

NCT05352269Phase 1UnknownPrimary

Safety and Tolerability of FMT Capsules in Healthy Volunteers

NCT05078073Not ApplicableUnknown

HBOT in the Treatment and Prevention of aGVHD

NCT02175615CompletedPrimary

Pharmacological Predictors of Successful Cyclosporine Acute GVHD Prophylaxis in Children Undergoing HSCT

NCT03339297Phase 2Completed

An Open-Label Study of Defibrotide for the Prevention of Acute Graft-versus-Host-Disease (AGvHD)

NCT03172455UnknownPrimary

Early Access Program Using Alpha 1 Antitrypsin Infusion for Patients With Steroid Refractory Acute GvHD After Hematopoietic Stem Cell Transplantation (HSCT)

NCT03764228Not ApplicableUnknownPrimary

Human Amniotic Epithelial Cells Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation

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