Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

26.7%

4 terminated out of 15 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

13%

2 trials in Phase 3/4

Results Transparency

150%

6 of 4 completed with results

Key Signals

6 with results50% success

Data Visualizations

Phase Distribution

12Total
P 1 (5)
P 2 (5)
P 3 (2)

Trial Status

Terminated4
Completed4
Unknown3
Recruiting3
Not Yet Recruiting1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (15)

Showing 15 of 15 trials
NCT06222580Phase 1RecruitingPrimary

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

NCT05024552Phase 1RecruitingPrimary

Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML

NCT01760655Phase 2CompletedPrimary

Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies

NCT07162116Phase 1RecruitingPrimary

A Study to Evaluate the Effect of XY0206 on the QTc Interval in Chinese Healthy Participants

NCT03333486Phase 2Terminated

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

NCT03735875Phase 1TerminatedPrimary

Venetoclax and Quizartinib in Treating Patients With FLT3-mutated Recurrent or Refractory Acute Myeloid Leukemia

NCT01578109Phase 1CompletedPrimary

Sorafenib Tosylate Before and After Donor Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia

NCT05876832Phase 3Not Yet RecruitingPrimary

A Study of XY0206 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory AML With FLT3-ITD-Mutation (ALIVE)

NCT01028716Phase 2Terminated

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

NCT05596968UnknownPrimary

The Gut Microbiome and Sorafenib Maintenance Therapy in FLT3-ITD Positive AML After Allo-HSCT

NCT05596981UnknownPrimary

The Gut Microbiome in FLT3-ITD+ AML Undergoing Allo-HSCT With Or Without Sorafenib Maintenance After Allo-HSCT

NCT01253070Phase 2CompletedPrimary

Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia

NCT04788420Completed

Influence of Co-existing Mutations on Sorafenib Maintenance Therapy After Allo-HSCT for Patients With FLT3-ITD AML

NCT04174612Phase 3UnknownPrimary

AML Patients Bearing FLT3 Mutations Based on Peripheral Blast Clearance

NCT02634827Phase 2TerminatedPrimary

Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation

Showing all 15 trials

Research Network

Activity Timeline