Key Insights

Highlights

No notable highlights available yet

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

17.9%

5 terminated out of 28 trials

Success Rate

16.7%

-69.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

100%

1 of 1 completed with results

Key Signals

1 with results

Data Visualizations

Phase Distribution

27Total
Early P 1 (2)
P 1 (23)
P 2 (2)

Trial Status

Recruiting17
Terminated5
Unknown2
Completed1
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

16.7%

Benchmark: 86.5%

Based on 1 completed trials

Clinical Trials (28)

Showing 20 of 20 trials
NCT07011004Phase 1RecruitingPrimary

A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia

NCT04716452Phase 1Recruiting

Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT04347616Phase 1TerminatedPrimary

Natural Killer-cell Therapy for Acute Myeloid Leukemia

NCT06459024Recruiting

Master Framework For Relapse or Refractory Acute Myeloid Leukemia

NCT06017258Phase 1Recruiting

A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

NCT06372717Phase 1RecruitingPrimary

A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

NCT04914845Phase 1Completed

KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia

NCT05317403Phase 1Recruiting

Venetoclax to Augment Epigenetic Modification and Chemotherapy

NCT05105152Phase 1Recruiting

PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

NCT06680752Phase 1Recruiting

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

NCT04678336Phase 1Terminated

CD123 Redirected T Cells for AML in Pediatric Subjects

NCT05211570Phase 1RecruitingPrimary

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT06281847Phase 1Not Yet Recruiting

An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia

NCT03766126Phase 1Active Not Recruiting

Lentivirally Redirected CD123 Autologous T Cells in AML

NCT06802315Phase 2Recruiting

Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)

NCT06128044Phase 1Terminated

CRISPR-Edited Allogeneic Anti-CLL-1 CAR-T Cell Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT05949125Phase 1Recruiting

Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies

NCT06297941Phase 1Recruiting

Study of REM-422 in Patients With AML or Higher Risk MDS

NCT06201247Early Phase 1Recruiting

Off-the-shelf CD123 CAR-NK for R/R AML

NCT05190471Phase 1Recruiting

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

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