Key Insights

Highlights

Success Rate

86% trial completion

Published Results

13 trials with published results (34%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

5.3%

2 terminated out of 38 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

108%

13 of 12 completed with results

Key Signals

13 with results86% success

Data Visualizations

Phase Distribution

37Total
Not Applicable (3)
Early P 1 (1)
P 1 (12)
P 2 (19)
P 3 (2)

Trial Status

Completed12
Active Not Recruiting8
Recruiting7
Unknown6
Terminated2
Withdrawn2

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (38)

Showing 20 of 20 trials
NCT03670966Phase 1Recruiting

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT03192397Phase 1Active Not RecruitingPrimary

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

NCT03286530Phase 2Active Not Recruiting

Ruxolitinib + Allogeneic Stem Cell Transplantation in AML

NCT06440135Phase 1Recruiting

Ziftomenib Maintenance Post Allo-HCT

NCT03494569Phase 1Suspended

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT05917405Phase 2RecruitingPrimary

Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCT

NCT04062266Phase 2Active Not RecruitingPrimary

AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission

NCT05224661Active Not RecruitingPrimary

Molecular Evaluation of AML Patients After Stem Cell Transplant to Understand Relapse Events

NCT03560752Phase 1Active Not Recruiting

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

NCT07163793Phase 2RecruitingPrimary

Pilot Study of Reduced Venetoclax Exposure

NCT05236764Not ApplicableActive Not Recruiting

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

NCT02506933Phase 2Active Not Recruiting

Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant

NCT02446964Phase 1Completed

Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

NCT02220985Phase 2Completed

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

NCT05794880Not ApplicableRecruiting

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

NCT02566304Phase 2Completed

Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

NCT04232241Phase 2Active Not RecruitingPrimary

Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia

NCT06462365Phase 1Recruiting

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

NCT01823198Phase 1Completed

Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies

NCT04712942Phase 2CompletedPrimary

Treatment of MDS/AML Patients With an Impending Hematological Relapse With AZA or ATA and Pevonedistat

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