Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.9%

5 terminated out of 42 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

60%

3 of 5 completed with results

Key Signals

3 with results50% success

Data Visualizations

Phase Distribution

39Total
Early P 1 (3)
P 1 (29)
P 2 (7)

Trial Status

Recruiting21
Terminated5
Completed5
Unknown4
Active Not Recruiting3
Not Yet Recruiting3

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (42)

Showing 20 of 20 trials
NCT07374029Phase 1Recruiting

Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML

NCT04898894Phase 1Active Not Recruiting

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

NCT07011004Phase 1Recruiting

A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia

NCT04716452Phase 1RecruitingPrimary

Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT05735184Phase 1Recruiting

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

NCT06459024RecruitingPrimary

Master Framework For Relapse or Refractory Acute Myeloid Leukemia

NCT06017258Phase 1Recruiting

A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

NCT06372717Phase 1Recruiting

A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

NCT04914845Phase 1Completed

KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia

NCT05317403Phase 1RecruitingPrimary

Venetoclax to Augment Epigenetic Modification and Chemotherapy

NCT05597306Phase 1Recruiting

Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT05105152Phase 1Recruiting

PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

NCT06552416Phase 1RecruitingPrimary

Safety of MT-401-OTS in Patients With Relapsed AML or MDS

NCT06680752Phase 1RecruitingPrimary

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

NCT06906380Not Yet RecruitingPrimary

A Long-term Follow-up Study of Patients With ARD103 CAR-T Cell Therapies

NCT04678336Phase 1TerminatedPrimary

CD123 Redirected T Cells for AML in Pediatric Subjects

NCT05211570Phase 1Recruiting

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT06281847Phase 1Not Yet RecruitingPrimary

An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia

NCT07157514Phase 2Not Yet Recruiting

Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML

NCT02438761Phase 2Terminated

PF-05212384 (PKI-587) for t-AML/MDS or de Novo Relapsed or Refractory Acute Myeloid Leukemia (AML) (LAM-PIK)

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