Key Insights

Highlights

Success Rate

63% trial completion

Published Results

44 trials with published results (20%)

Research Maturity

77 completed trials (35% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

20.4%

45 terminated out of 221 trials

Success Rate

63.1%

-23.5% vs benchmark

Late-Stage Pipeline

12%

26 trials in Phase 3/4

Results Transparency

57%

44 of 77 completed with results

Key Signals

44 with results63% success45 terminated

Data Visualizations

Phase Distribution

190Total
Not Applicable (9)
Early P 1 (5)
P 1 (90)
P 2 (60)
P 3 (25)
P 4 (1)

Trial Status

Completed77
Recruiting46
Terminated45
Not Yet Recruiting22
Unknown11
Active Not Recruiting9

Trial Success Rate

63.1%

Benchmark: 86.6%

Based on 77 completed trials

Clinical Trials (221)

Showing 20 of 20 trials
NCT07841002Phase 1Not Yet Recruiting

CLL-1-Targeted In Vivo CAR-T Cell Immunotherapy for Relapsed/Refractory Acute Myeloid Leukemia

NCT07458542CompletedPrimary

Effectiveness and Safety of ONUREG (Oral Azacitidine) in Chinese Patients With Acute Myeloid Leukemia

NCT04429191Phase 1Completed

JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation

NCT06398457Early Phase 1Recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

NCT04266795Phase 2CompletedPrimary

A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy

NCT07828535Phase 1Not Yet RecruitingPrimary

Liposomal Mitoxantrone Plus Azacitidine and Venetoclax in Newly Diagnosed Elderly or Unfit AML

NCT06268574Phase 2TerminatedPrimary

Safety and Efficacy of RVU120 for Treatment of Relapsed/Refractory AML

NCT03849651Phase 2Active Not Recruiting

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

NCT04547062Phase 1CompletedPrimary

Monocentric Phase 1 Study With Escalation of Doses of Tocilizumab in Combination With Chemotherapy (Idarubicin and Cytarabine) in Patients With Acute Myeloblastic Leukemia (AML)

NCT05520567Phase 1Active Not RecruitingPrimary

A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia

NCT07813390Phase 2Enrolling By InvitationPrimary

Homoharringtonine, Lisaftoclax, and Azacitidine for AML After Venetoclax-Based Therapy Failure

NCT07754799Phase 2Not Yet RecruitingPrimary

A Randomized Trial of Venetoclax-Based Induction Intensity in Newly Diagnosed Acute Myeloid Leukemia

NCT07053020Phase 1Not Yet RecruitingPrimary

A Phase 1 Open-Label, Dose-Ranging Safety and Pharmacokinetics Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML)

NCT06811233Phase 2RecruitingPrimary

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

NCT07784309Phase 1Enrolling By Invitation

A Clinical Study of HY035 Cell Injection in the Treatment of CD7-positive Relapsed or Refractory Hematologic Malignancies

NCT07777471Not ApplicableNot Yet RecruitingPrimary

Improving Delivery of Aging-Related Supportive Care for Older Adults With Acute Myeloid Leukemia

NCT07780565Phase 1Not Yet RecruitingPrimary

Study of Monzosertib In Patients With R/R AML Or High-Risk Myelodysplastic Syndrome

NCT07007312Phase 3RecruitingPrimary

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

NCT07565220Phase 1Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

NCT07302776Phase 1Recruiting

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

Scroll to load more

Research Network

Activity Timeline