Key Insights

Highlights

Success Rate

63% trial completion

Published Results

44 trials with published results (20%)

Research Maturity

75 completed trials (35% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

20.5%

44 terminated out of 215 trials

Success Rate

63.0%

-23.5% vs benchmark

Late-Stage Pipeline

12%

26 trials in Phase 3/4

Results Transparency

59%

44 of 75 completed with results

Key Signals

44 with results63% success44 terminated

Data Visualizations

Phase Distribution

184Total
Not Applicable (8)
Early P 1 (5)
P 1 (86)
P 2 (59)
P 3 (25)
P 4 (1)

Trial Status

Completed75
Recruiting45
Terminated44
Not Yet Recruiting19
Unknown12
Active Not Recruiting11

Trial Success Rate

63.0%

Benchmark: 86.6%

Based on 75 completed trials

Clinical Trials (215)

Showing 20 of 20 trials
NCT05188170Phase 1RecruitingPrimary

Niclosamide in Pediatric Patients With Relapsed and Refractory AML

NCT07761533Phase 1RecruitingPrimary

PBSS1113 in Combination With Azacitidine to Treat Patients With AML/MDS

NCT07754799Phase 2Not Yet RecruitingPrimary

A Randomized Phase II Selection Trial of Venetoclax-Based Induction Intensity in Newly Diagnosed Acute Myeloid Leukemia

NCT05092451Phase 1Recruiting

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

NCT07670130RecruitingPrimary

Venetoclax TDM in Newly Diagnosed AML: Exposure-Response and Prognosis

NCT06641648Phase 1RecruitingPrimary

A Phase I Single-arm Clinical Study of Donor NK Cells Infusion Combined With Low-dose Interleukin-2 in the Treatment of Acute Myeloid Leukemia Relapse After Allogeneic Hematopoietic Stem Cell Transplantation.

NCT07735117Phase 3Not Yet RecruitingPrimary

Mitoxantrone Hydrochloride Liposome, Cytarabine, G-CSF Plus Venetoclax vs. Azacitidine Plus Venetoclax for MDS-IB2 and Secondary/Elderly AML

NCT07007312Phase 3RecruitingPrimary

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

NCT03849651Phase 2Active Not Recruiting

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

NCT04603001Phase 1Active Not RecruitingPrimary

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

NCT02416388Phase 2RecruitingPrimary

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR

NCT02752035Phase 3CompletedPrimary

A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

NCT07464951Phase 1RecruitingPrimary

CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia

NCT07686965Phase 3Not Yet RecruitingPrimary

Lisaftoclax Plus Azacitidine Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients at High Risk of Relapse

NCT07680868RecruitingPrimary

Caris Chromoseq Data Collection

NCT07565220Phase 1Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

NCT07668557Phase 1RecruitingPrimary

Anti-CD33-CLL1 CAR-T Cells (ICG415) for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia

NCT05756777Phase 1RecruitingPrimary

A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

NCT06707493Phase 2Recruiting

Ivosidenib as Post-HSCT Maintenance for AML

NCT07651163Phase 2Enrolling By InvitationPrimary

Comparing the Efficacy of LDA, LHAA, and LA Regimens in Young Adults With Intermediate- and High-Risk Acute Myeloid Leukemia Eligible for Intensive Chemotherapy

Scroll to load more

Research Network

Activity Timeline