Key Insights

Highlights

Success Rate

64% trial completion

Published Results

42 trials with published results (21%)

Research Maturity

75 completed trials (37% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

20.7%

42 terminated out of 203 trials

Success Rate

64.1%

-22.4% vs benchmark

Late-Stage Pipeline

12%

24 trials in Phase 3/4

Results Transparency

56%

42 of 75 completed with results

Key Signals

42 with results64% success42 terminated

Data Visualizations

Phase Distribution

174Total
Not Applicable (8)
Early P 1 (5)
P 1 (83)
P 2 (54)
P 3 (23)
P 4 (1)

Trial Status

Completed75
Terminated42
Recruiting37
Not Yet Recruiting18
Unknown12
Active Not Recruiting11

Trial Success Rate

64.1%

Benchmark: 86.5%

Based on 75 completed trials

Clinical Trials (203)

Showing 20 of 20 trials
NCT04872595Phase 2Active Not RecruitingPrimary

A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant

NCT05092451Phase 1Recruiting

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

NCT07565220Phase 1Not Yet Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

NCT05833438Phase 2Active Not RecruitingPrimary

Venetoclax in Combination With 5 Days Azacitidine in Untreated AML Patients, Not Eligible for Standard Induction Therapy

NCT04639024Phase 2TerminatedPrimary

ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN

NCT06707493Phase 2Recruiting

Ivosidenib as Post-HSCT Maintenance for AML

NCT06811233Phase 2RecruitingPrimary

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

NCT03188874RecruitingPrimary

Clinical AML Registry and Biomaterial Database of the Study Alliance Leukemia (SAL)

NCT07537738RecruitingPrimary

Leukemia Stem Cell-based Assay to Predict Relapse and Survival in Patients With Acute Myeloid Leukemia

NCT07302776Phase 1Not Yet Recruiting

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

NCT07532824Phase 1RecruitingPrimary

Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS

NCT07469046Phase 3Not Yet RecruitingPrimary

VAH vs VA in Newly Diagnosed Elderly AML

NCT03849651Phase 2Active Not Recruiting

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

NCT07007312Phase 3RecruitingPrimary

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

NCT04102020Phase 3CompletedPrimary

A Study of Oral Venetoclax Tablets and Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy

NCT07507825Phase 2Not Yet RecruitingPrimary

Exploratory Study of Venetoclax, Homoharringtonine, Azacitidine Plus G-CSF for Newly Diagnosed AML (VHAG)

NCT07505160Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Lisafotoclax Plus Decitabine and Homoharringtonine in Venetoclax/Azacitidine Pretreated AML Patients

NCT07500441RecruitingPrimary

Digital PCR of CHIP and MR for MRD Monitoring After Allo-HSCT in AML

NCT05756777Phase 1RecruitingPrimary

A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

NCT07463651Phase 3RecruitingPrimary

MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib

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Research Network

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