Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

11.5%

3 terminated out of 26 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

15%

4 trials in Phase 3/4

Results Transparency

0%

0 of 3 completed with results

Key Signals

50% success

Data Visualizations

Phase Distribution

21Total
Not Applicable (2)
P 1 (7)
P 2 (8)
P 3 (4)

Trial Status

Recruiting8
Unknown5
Terminated3
Not Yet Recruiting3
Completed3
Active Not Recruiting2

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT07478991Phase 3Not Yet RecruitingPrimary

Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)

NCT05906914Phase 2CompletedPrimary

Cladribine Plus Homoharringtonine and Cytarabine Regimen (CHA) for de Novo Acute Myeloid Leukemia

NCT05001828Phase 1Active Not RecruitingPrimary

Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia

NCT06532552Phase 2RecruitingPrimary

Comparison of VA (Venetoclax, Azacitidine), VACl (VA, Cladribine), VACh (VA, Chidamide), and Alternating VACl/VACh in Newly Diagnosed Acute Myeloid Leukemia

NCT06513273Recruiting

Observational Study on the Outcome of AML Patients Treated With New Drugs in Real-life (BoxTrial)

NCT06199557Phase 1RecruitingPrimary

A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS Patients

NCT03766126Phase 1Active Not Recruiting

Lentivirally Redirected CD123 Autologous T Cells in AML

NCT06449482Phase 1TerminatedPrimary

Selinexor、Venetoclax and Azactidine in the Treatment of ND AML Patients Who Are Not Eligible for Intense Chemotherapy

NCT04050280Phase 2RecruitingPrimary

CLAG-GO for Patients With Persistent, Relapsed or Refractory AML

NCT05133882Phase 1RecruitingPrimary

A Phase Ⅰb/Ⅱ Clinical Study of Clifutinib Besylate Combined With Chemotherapy in the Treatment of Newly Diagnosed AML

NCT06652438Phase 3RecruitingPrimary

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

NCT05674539Phase 3Enrolling By InvitationPrimary

Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome

NCT06200441WithdrawnPrimary

Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease

NCT05601726Phase 1RecruitingPrimary

First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients

NCT05703126Not ApplicableRecruitingPrimary

Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML

NCT03902665Phase 2CompletedPrimary

Up-front Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients Aged 65-75

NCT05988047CompletedPrimary

Analysis of CMTM6 Expression in Patients With Acute Myeloid Leukemia

NCT06285136Phase 2Not Yet RecruitingPrimary

Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult

NCT06252584Phase 1Not Yet RecruitingPrimary

Multi-peptide Vaccination Adjuvanted With XS15 in Acute Myeloid Leukemia Patients

NCT04425655Phase 2TerminatedPrimary

Fludarabine in Combination With Daunorubicin and Cytarabine Liposome in Newly-diagnosed Acute Myeloid Leukemia.

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