Key Insights

Highlights

Success Rate

74% trial completion

Published Results

286 trials with published results (19%)

Research Maturity

538 completed trials (36% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.9%

191 terminated out of 1478 trials

Success Rate

73.8%

-12.8% vs benchmark

Late-Stage Pipeline

8%

124 trials in Phase 3/4

Results Transparency

53%

286 of 538 completed with results

Key Signals

286 with results74% success191 terminated

Data Visualizations

Phase Distribution

1,287Total
Not Applicable (109)
Early P 1 (23)
P 1 (591)
P 2 (440)
P 3 (106)
P 4 (18)

Trial Status

Completed538
Recruiting283
Terminated191
Unknown190
Active Not Recruiting123
Not Yet Recruiting69

Trial Success Rate

73.8%

Benchmark: 86.6%

Based on 538 completed trials

Clinical Trials (1478)

Showing 20 of 20 trials
NCT07437950Phase 2RecruitingPrimary

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

NCT05317494CompletedPrimary

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in Greece

NCT05457010Phase 1Active Not RecruitingPrimary

Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome.

NCT07581002Phase 2RecruitingPrimary

A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

NCT05334069Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

NCT05583552Phase 2Completed

Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy

NCT07304011Phase 2RecruitingPrimary

Olutasidenib With Azacitidine Followed by Olutasidenib Maintenance for the Treatment of IDH1-mutated Acute Myeloid Leukemia in Patients With Prior Treatment With Venetoclax Plus a Hypomethylating Agent

NCT07755202Phase 2Not Yet RecruitingPrimary

Gilteritinib-Azacitidine-Venetoclax Combination Therapy in Patients With Relapsed/Refractory Leukemia

NCT01494103Phase 1Active Not Recruiting

Administration of Donor T Cells With the Caspase-9 Suicide Gene

NCT06055621Phase 2SuspendedPrimary

Evaluation of DASATINIB Monotherapy Efficacy in Acute Myeloid Leukemia Patients Refractory to VENETOCLAX-AZACITIDINE

NCT06419634Phase 1TerminatedPrimary

Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT06484062Phase 1RecruitingPrimary

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

NCT01985061Phase 2Completed

Evaluation of 3 Different Doses of IV Busulfan

NCT05554419Phase 2Not Yet RecruitingPrimary

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

NCT07634536Phase 2Not Yet RecruitingPrimary

Automated Total Marrow and Lymphoid Irradiation for Allogeneic Hematopoietic Cell Transplant

NCT07570056Not Yet Recruiting

Use of Electrical Bioimpedance in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients (Bioimpedance)

NCT06197672Phase 1SuspendedPrimary

Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant

NCT05424562TerminatedPrimary

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in Canada

NCT03187288Phase 1CompletedPrimary

Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS

NCT03597321Phase 2Active Not RecruitingPrimary

Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AML

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