Key Insights

Highlights

Success Rate

76% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

9.3%

4 terminated out of 43 trials

Success Rate

76.5%

-10.1% vs benchmark

Late-Stage Pipeline

9%

4 trials in Phase 3/4

Results Transparency

69%

9 of 13 completed with results

Key Signals

9 with results76% success

Data Visualizations

Phase Distribution

34Total
Not Applicable (4)
P 1 (11)
P 2 (15)
P 3 (2)
P 4 (2)

Trial Status

Completed13
Recruiting8
Unknown8
Active Not Recruiting6
Terminated4
Not Yet Recruiting2

Trial Success Rate

76.5%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (43)

Showing 20 of 20 trials
NCT05442515Phase 1Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

NCT05827549Phase 2RecruitingPrimary

Evaluation of Treatment Efficacy According to Risk Group in Relapsed Childhood Acute Lymphoblastic Leukemia

NCT07346105Unknown

Orca-T Expanded Access Program Study for Patients With Advanced Hematologic Malignancies

NCT03610438Phase 2Active Not RecruitingPrimary

Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

NCT07254793Phase 1Not Yet RecruitingPrimary

Prophylactic and Therapeutic DLI-X for Leukemia Relapse After HCT

NCT06551584Phase 1Recruiting

Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT

NCT07634653Not ApplicableNot Yet Recruiting

Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)

NCT04013685Phase 1Active Not Recruiting

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

NCT06681363Recruiting

Creation of a Biocollection of Patients With Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelodysplastic Syndrome (MDS) Monitored at the Nantes University Hospital

NCT05322850Phase 1Suspended

Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)

NCT05535855Phase 1RecruitingPrimary

UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1

NCT05316701Phase 3Active Not Recruiting

Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

NCT00590915Unknown

Erwinase Master Treatment Protocol

NCT04167683Active Not Recruiting

Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant

NCT05792007Not ApplicableRecruitingPrimary

Study of the Medullary Microenvironment in Acute Childhood Leukemia

NCT05150561Active Not Recruiting

Muscle Dysfunction in Patients With Haematological Diseases

NCT04669210Phase 2Completed

PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT

NCT03448393Phase 1Completed

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

NCT05959720RecruitingPrimary

Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil

NCT05166135Completed

Latin American Real-world Study in Acute Leukemia

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