Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

25.0%

9 terminated out of 36 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

17%

6 trials in Phase 3/4

Results Transparency

100%

9 of 9 completed with results

Key Signals

9 with results50% success

Data Visualizations

Phase Distribution

33Total
Not Applicable (3)
P 1 (16)
P 2 (8)
P 3 (5)
P 4 (1)

Trial Status

Completed9
Terminated9
Recruiting6
Withdrawn4
Unknown3
Not Yet Recruiting3

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (36)

Showing 20 of 20 trials
NCT07535008Not ApplicableRecruiting

Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease

NCT06444022Phase 1WithdrawnPrimary

hAESCs Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation

NCT03158896Phase 1CompletedPrimary

Evaluation of Umbilical Cord-Derived Wharton's Jelly Stem Cells for the Treatment of Acute Graft Versus Host Disease

NCT06026371Phase 2Active Not RecruitingPrimary

Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation

NCT07047456Phase 3RecruitingPrimary

Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies Post UCBT

NCT07285889Phase 1RecruitingPrimary

First-Line Jaktinib for Acute Graft-Versus-Host Disease (aGVHD)

NCT03057054Phase 3Active Not RecruitingPrimary

Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant

NCT05443425Phase 1RecruitingPrimary

Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

NCT05921305Phase 3RecruitingPrimary

Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD

NCT03491215Phase 1CompletedPrimary

Study of Pharmacokinetics, Activity and Safety of Ruxolitinib in Pediatric Patients With Grade II-IV Acute Graft vs. Host Disease

NCT06904599Phase 2RecruitingPrimary

Efficacy of Human Chorionic Gonadotropin in Acute GVHD Treatment

NCT04910152Phase 1TerminatedPrimary

Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD

NCT00032773Phase 1TerminatedPrimary

Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHD

NCT06480630Phase 2Not Yet RecruitingPrimary

Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases

NCT06473909Phase 2Not Yet RecruitingPrimary

Combination of Steroid and Humanized CD25 Monoclonal Antibody as First-line Therapy for aGVHD

NCT06386445Not Yet Recruiting

Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT: Cohort Study

NCT04280471Phase 1WithdrawnPrimary

Fecal Microbiota Transplantation for the Treatment of Severe Acute Gut Graft-Versus-Host Disease

NCT05823675Phase 1UnknownPrimary

Safety and Clinical Activity of Itolizumab in aGVHD

NCT04006652Phase 1TerminatedPrimary

ApoGraft for the Prevention of Acute Graft Versus Host Disease in Haploidentical Hematopoietic Cell Transplant Recipients

NCT04095858Phase 3Terminated

Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005)

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