NCT00229047

Brief Summary

We, the researchers at Lawson Health Research Institute, propose to investigate the impact of surgical ischemia and reperfusion on skeletal muscle microcirculation using a hand-held microscope.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2005

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2005

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

September 27, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 29, 2005

Completed
5.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

August 25, 2017

Status Verified

August 1, 2017

Enrollment Period

5.7 years

First QC Date

September 27, 2005

Last Update Submit

August 24, 2017

Conditions

Ischemia

Keywords

Ischemic PreconditioningMicrovascular PerfusionInflammationIschemia and ReperfusionChronic Limb Ischemia

Study Arms (1)

Vein Stripping

Patients undergoing elective varicose vein stripping in our vascular OR. Observe circulation in the exposed soleus/gastrocnemius muscle.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients undergoing routine and elective varicose vein stripping.

You may qualify if:

  • Patients undergoing femoral distal bypass procedures for chronic limb ischemia

You may not qualify if:

  • Any severe comorbid conditions (i.e., chronic obstructive pulmonary disease \[COPD\])

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Lawson Health Research Institute

London, Ontario, N6A 4G5, Canada

Location

MeSH Terms

Conditions

IschemiaInflammation

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Amit Badhwar, PhD

    Scientist

    STUDY DIRECTOR

  • Tom Forbes, MD

    Vascular Surgeon

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 27, 2005

First Posted

September 29, 2005

Study Start

April 1, 2005

Primary Completion

December 1, 2010

Study Completion

December 1, 2011

Last Updated

August 25, 2017

Record last verified: 2017-08

Locations

CA(1)